Subacute sclerosing panencephalitis in pregnancy

The Lancet Infectious Diseases
Michael H ChiuMarcus W Koch

Abstract

We present a case of subacute sclerosing panencephalitis that developed in a previously healthy 29-year-old pregnant woman who had returned from a trip to rural India shortly before the onset of symptoms. She was admitted to hospital at 27 weeks' gestation with a history of cognitive decline and difficulty completing simple tasks. She had no clinical signs of infection. The working diagnosis was autoimmune encephalitis, although extensive investigations did not lead to a final classifying diagnosis. The patient became comatose and developed hypertension, and an emergency caesarean section was done at 31 weeks to deliver the child, who seemed healthy. The patient died about 6 weeks after the onset of symptoms. The patient was found to have had subacute sclerosing panencephalitis at autopsy. In this Grand Round, we review the clinical features and treatment of subacute sclerosing panencephalitis, and the epidemiological and public health aspects of the case.

References

Sep 1, 1989·International Journal of Epidemiology·Y OkunoI Kitamura
Dec 1, 1988·Archives of Neurology·I WirguinO Abramsky
Mar 26, 1973·JAMA : the Journal of the American Medical Association·P J Landrigan, J J Witte
May 1, 1993·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·M M MustafaJ D Siegel
Dec 10, 1999·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·A BitnunR Tellier
Sep 29, 2000·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·S JayawantJ Ellis
Aug 6, 2002·Journal of Neurovirology·L JinE Miller
Aug 27, 2002·Emerging Infectious Diseases·Paul A RotaWilliam J Bellini
Jan 28, 2003·Journal of Child Neurology·Masaharu HayashiYoshio Morimatsu
Dec 19, 2003·Neuropediatrics·S ViekerH Hartmann
Feb 24, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·L Bennetto, N Scolding
Apr 24, 2004·The Journal of Infectious Diseases·Graham A TipplesUNKNOWN Canadian Measles Surveillance Program
Oct 7, 2004·Pediatric Neurology·Ingrid E B Tuxhorn
Nov 24, 2004·Archives of Disease in Childhood·C MillerE Miller
May 17, 2005·Virus Research·Bertus K Rima, W Paul Duprex
Oct 15, 2005·Journal of Neuroimmunology·Sibel P YentürGüher Saruhan-Direskeneli
May 15, 2007·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Maja SantakDubravko Forcić
Jul 27, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S Praveen-kumarS Ravishankar
Nov 27, 2007·International Journal of Epidemiology·H CampbellE Miller
Dec 1, 2007·WormBook : the Online Review of C. Elegans Biology·Bhagwati P GuptaNansheng Chen
Feb 19, 2008·Pediatric Neurology·Vinod SharmaMichael Eisenhut
Jun 28, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Allan R TunkelUNKNOWN Infectious Diseases Society of America
Oct 11, 2008·Journal of Neurology·Ravindra Kumar Garg
Nov 20, 2008·Journal of Neurovirology·Yoshito IshizakiToshiro Hara
Jan 13, 2010·Human Genetics·Yoshito IshizakiToshiro Hara
Apr 7, 2010·American Journal of Reproductive Immunology : AJRI·Gil Mor, Ingrid Cardenas
Jun 22, 2010·Developmental Medicine and Child Neurology·Jose GutierrezBarbara S Koppel
May 11, 2011·Pediatric Neurology·Ronly Har-EvenTzvy Bistritzer
Jun 17, 2011·The Journal of Infectious Diseases·Paul A RotaDavid Featherstone
Aug 15, 2012·Seminars in Pediatric Neurology·Renee Buchanan, Daniel J Bonthius
Aug 21, 2012·The Australasian Medical Journal·Bhawna MalikAkshay Sharma
Mar 19, 2013·Neuropediatrics·Ibrahim Etem PiskinAkın Iscan
Mar 28, 2013·Case Reports in Neurological Medicine·Sandhya Ravikumar, John Ross Crawford
Apr 1, 2014·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Takashi OhyaToyojiro Matsuishi
May 29, 2014·QJM : Monthly Journal of the Association of Physicians·D L FisherT Solomon

❮ Previous
Next ❯

Citations

Apr 8, 2017·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Kristen A WendorfKathleen Harriman
Nov 1, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Bárbara GomesMatteo Porotto
Jan 24, 2020·The American Journal of Tropical Medicine and Hygiene·Praveen Kumar SharmaShinu Singla
Jun 27, 2019·Reviews in Medical Virology·Ravindra Kumar GargRavi Uniyal

❮ Previous
Next ❯

Methods Mentioned

BETA
lavage
genotyping
transmission electron microscopy
biopsies
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved