Subacute sclerosing panencephalitis: propagation of measles virus from brain biopsy in tissue culture

Science
T T ChenJ Mealey

Abstract

Measles virus was propagated in monolayer cultures established from brain tissue of a patient with subacute sclerosing panencephalitis. Syncytial cells were rendered fluorescent with measles specific antiserums only, by means of an indirect technique. The ultrastructural appearance of the microtubular aggregates was identical in brain tissue and in the cultured cells. Fusion experiments produced a cytopathic effect in humnan embryonic kidney and VERO cell cultures. The virus was identified by hemiagglutination-inhibition, but only in the supernatant of disrupted cultured cells.

References

Nov 1, 1968·Proceedings of the Society for Experimental Biology and Medicine·J V Baublis, F E Payne

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Citations

Jan 1, 1971·Arthritis and Rheumatism·F B HollingerW E Rawls
May 1, 1972·Arthritis and Rheumatism·E R HurdM Ziff
Jun 1, 1978·Arthritis and Rheumatism·M V ViolaP D Duffy
Sep 13, 2001·Mental Retardation and Developmental Disabilities Research Reviews·P R Dyken
Jan 1, 1971·Zeitschrift für Neurologie·H Thormar
Jan 1, 1972·Acta Neuropathologica·M G HadfieldW I Rosenblum
Jan 1, 1972·Archiv für die gesamte Virusforschung·P E Gibson, T M Bell
Mar 1, 1971·Naika. Internal medicine·H Tokuomi, T Tsuda
Aug 1, 1972·Journal of the Neurological Sciences·T M BellT C Noble
Apr 8, 1971·The New England Journal of Medicine·T W Chang
Jul 8, 1971·The New England Journal of Medicine·K L Gerson, R H Haslam
Jan 1, 1970·Annals of the Rheumatic Diseases·W L NortonL Robison
Jul 1, 1970·Annals of the Rheumatic Diseases·H R Schumacher
May 23, 1970·British Medical Journal·M PaneliusU K Rinne
May 1, 1970·Postgraduate Medical Journal·H A Reimann
Jun 1, 1973·Japanese Journal of Medical Science & Biology·A ShishidoT A Sato
Oct 1, 1972·Japanese Journal of Medical Science & Biology·Y DoiT Koto
Jun 1, 1975·American Journal of Ophthalmology·A G DeVoe
Jun 1, 1970·American Journal of Ophthalmology·L E Zimmerman
Jun 1, 1975·The Journal of Comparative Neurology·D H GildenH Koprowski
Nov 21, 1970·Lancet·T PincusJ A Bellanti
Aug 1, 1971·Seminars in Arthritis and Rheumatism·J M Nardo, W L Norton
Nov 1, 1976·Seminars in Arthritis and Rheumatism·M E Gershwin, A D Steinberg
Jan 1, 1981·Annals of Neurology·I M ParhadP Swoveland

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