Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome

Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Graeme E CorrellRonald E Harbut

Abstract

Complex Regional Pain Syndrome (CRPS) is a disorder that can be accompanied by severe pain that is often both chronic and resistant to conventional therapy. Harbut and Correll previously reported the successful treatment of a 9-year case of intractable Type I CRPS with an intravenous inpatient infusion of ketamine in an adult female patient. The purpose of this study was to ascertain if indeed the use of subanesthetic inpatient infusions of ketamine provide meaningful improvements in pain scores, and thus, quality of life, in patients suffering from CRPS. To achieve this objective we focused our analysis on the relief of pain obtained by patients undergoing this novel treatment option developed at Mackay Base Hospital, Queensland, Australia. Case notes of 33 patients whose CRPS pain was treated by the inpatient administration of a continuous subanesthetic intravenous infusion of ketamine were reviewed. The dose and duration of ketamine therapy and the degree and duration of relief obtained were recorded. Notable side effects were also recorded. The degree of relief obtained (immediately after the infusion) was assessed using pre- and posttreatment numeric pain scores. The duration of relief obtained (throughout the follow-up pe...Continue Reading

Associated Clinical Trials

Jul 17, 2015·Andrew Phillip Carlson

References

Nov 11, 1975·Anesthesia and Analgesia·J A KaplanE G gallagher
Dec 6, 1991·Science·J W OlneyM A Sesma
Mar 1, 1974·Anaesthesia·Y Ito, K Ichiyanagi
Jan 1, 1995·Anesthesia and Analgesia·S Pockett
Sep 1, 1994·The Clinical Journal of Pain·V HoffmannH Adriaensen
Mar 1, 1997·Acta Anaesthesiologica Scandinavica·P Klepstad, P C Borchgrevink
Mar 1, 1997·Acta Anaesthesiologica Scandinavica·L NikolajsenT S Jensen
Sep 1, 1997·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·A K MalhotraA Breier
Jan 14, 1999·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·J W NewcomerJ W Olney
Dec 10, 1999·Regional Anesthesia and Pain Medicine·K J Carpenter, A H Dickenson
Feb 25, 2000·Journal of Pain and Symptom Management·G J Bennett
Feb 25, 2000·Journal of Pain and Symptom Management·C N Sang
Jun 30, 2000·Clinical and Experimental Pharmacology & Physiology·M T Smith
Mar 22, 2001·Brain Research·V Jevtovic-TodorovicJ W Olney
Jul 20, 2002·The Journal of Pharmacology and Experimental Therapeutics·Timothy D Moran, Peter A Smith
Oct 10, 2002·Regional Anesthesia and Pain Medicine·Takahiro UshidaHiroshi Yamamoto
Apr 22, 2004·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Jahangir Maleki
Nov 30, 2006·Molecular Psychiatry·S R BornsteinJ Licinio

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Citations

Jan 12, 2007·Current Pain and Headache Reports·Sean Mackey, Steven Feinberg
Jul 6, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Sandra P KofflerRobert J Schwartzman
Jul 12, 2012·Journal of Palliative Medicine·Rosene D Pirrello
Jul 11, 2009·The Clinical Journal of Pain·Robert J SchwartzmanGuillermo M Alexander
Jan 22, 2010·The Clinical Journal of Pain·William T ZempskyJ Nathan Hagstrom
Mar 21, 2009·American Journal of Therapeutics·Eric S Hsu
Oct 13, 2012·Annals of Surgery·David BorsookDennis W Burke
Apr 2, 2010·BMC Neurology·Roberto S PerezUNKNOWN CRPS I task force
Feb 7, 2012·CNS Drugs·Sanjay J MathewJames W Murrough
Nov 1, 2012·Pain Management·Bassem Asaad, Peter Glass
Oct 15, 2013·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Qutaiba A TawficJohn Penning
Aug 15, 2013·Life Sciences·Carlos VenâncioFrancisco Peixoto
Feb 1, 2005·Anesthesiology·Charles B Berde, Alyssa Lebel
Apr 15, 2011·Regional Anesthesia and Pain Medicine·Stefan A W BouwenseOliver H G Wilder-Smith
May 28, 2010·Journal of Pain & Palliative Care Pharmacotherapy·Brian Jakubowicz, Musa Aner
Feb 3, 2012·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·R Norman Harden
Sep 24, 2011·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Sheetal Patil, Magdalena Anitescu
Feb 27, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Petr Cvrcek
Oct 30, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Alexander G MuntsJacobus J van Hilten
Jun 22, 2013·Current Medical Research and Opinion·Joseph PergolizziGiustino Varrassi
Feb 13, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ralph-Thomas KieferRobert J Schwartzman
Mar 15, 2006·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Graeme E Correll, Graham E Futter
Sep 12, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Adam EverettChester Buckenmaier
Feb 8, 2008·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Ralph-Thomas KieferRobert J Schwartzman
Jul 14, 2010·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Osama ElsewaisyJohn Monagle
Jul 6, 2007·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rollin M Gallagher
Feb 19, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Andrea SantamatoPietro Fiore
Jan 15, 2015·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Sara B ConnollyR Norman Harden
Jan 6, 2006·Pain Medicine : the Official Journal of the American Academy of Pain Medicine
Aug 9, 2005·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Rollin M Gallagher
Nov 20, 2012·The American Journal of Emergency Medicine·Andrew A HerringBradley W Frazee
Oct 9, 2012·The American Journal of Emergency Medicine·John R Richards, Rachel E Rockford
May 24, 2011·Foot and Ankle Clinics·Ashish Shah, John S Kirchner
Sep 29, 2009·The Journal of Pain : Official Journal of the American Pain Society·Baptiste BessièreGuy Simonnet
May 14, 2011·Pediatric Annals·David A Rosen, Joshua Dower
Oct 29, 2008·The Veterinary Clinics of North America. Small Animal Practice·Leigh A Lamont
Oct 29, 2008·The Veterinary Clinics of North America. Small Animal Practice·Karol A Mathews
Nov 30, 2006·Brain, Behavior, and Immunity·Guillermo M AlexanderRobert J Schwartzman
Dec 6, 2007·Anaesthesia·R Craven
Jun 15, 2007·Pain Practice : the Official Journal of World Institute of Pain·Ralph-Thomas KieferRobert Jay Schwartzman
Feb 20, 2007·Pain Practice : the Official Journal of World Institute of Pain·Vicente L Villanueva-PerezJose A De Andrés

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