Subarachnoid Hemorrhage in Mechanical Thrombectomy for Acute Ischemic Stroke: Analysis of the STRATIS Registry, Systematic Review, and Meta-Analysis.

Frontiers in Neurology
Hubert LeeVitor M Pereira

Abstract

Background: The indications for mechanical thrombectomy in acute ischemic stroke continue to broaden, leading neurointerventionalists to treat vessel occlusions at increasingly distal locations farther in time from stroke onset. Accessing these smaller vessels raises the concern of iatrogenic subarachnoid hemorrhage (SAH) owing to increasing complexity in device navigation and retrieval. This study aims to determine the prevalence of SAH following mechanical thrombectomy, associated predictors, and resulting functional outcomes using a multicenter registry and compare this with a systematic review and meta-analysis of the literature. Methods: Data from STRATIS (The Systematic Evaluation of Patients Treated with Neurothrombectomy Devices for Acute Ischemic Stroke) registry were analyzed dichotomized by the presence or absence of SAH after thrombectomy. Only patients with 24-h post-procedural neuroimaging were included (n = 841). Multivariable logistic regression was performed to identify significant predictors of SAH. A systematic review and random-effects meta-analysis was also conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analysis) protocol. Results: The prevalence of post-t...Continue Reading

References

Feb 1, 1981·Journal of Neurosurgery·H GiboR J Mitchell
Oct 12, 2010·Cardiovascular and Interventional Radiology·Gunther FeslHartmut Brueckmann
Nov 6, 2010·Stroke; a Journal of Cerebral Circulation·Zhong-Song ShiUNKNOWN UCLA Endovascular Stroke Therapy Investigators
Oct 13, 2011·Journal of Neurointerventional Surgery·Paolo MachiAlain Bonafé
Apr 12, 2012·Journal of Neurointerventional Surgery·Ansaar T RaiGerald Hobbs
Aug 2, 2012·Stroke; a Journal of Cerebral Circulation·Antoni DávalosUNKNOWN Solitaire Group
Apr 30, 2013·Journal of Neurointerventional Surgery·Aquilla S TurkImran Chaudry
Aug 3, 2013·Stroke; a Journal of Cerebral Circulation·Vitor M PereiraGerhard Schroth
Dec 18, 2014·The New England Journal of Medicine·Olvert A BerkhemerUNKNOWN MR CLEAN Investigators
Feb 12, 2015·The New England Journal of Medicine·Bruce C V CampbellUNKNOWN EXTEND-IA Investigators
Feb 12, 2015·The New England Journal of Medicine·Mayank GoyalUNKNOWN ESCAPE Trial Investigators
Feb 26, 2015·Stroke; a Journal of Cerebral Circulation·Dayu TengAlexander A Khalessi
Apr 18, 2015·The New England Journal of Medicine·Jeffrey L SaverUNKNOWN SWIFT PRIME Investigators
Apr 18, 2015·The New England Journal of Medicine·Tudor G JovinUNKNOWN REVASCAT Trial Investigators
May 8, 2015·Journal of Neurointerventional Surgery·Diogo C HaussenRaul G Nogueira
Sep 4, 2015·Stroke; a Journal of Cerebral Circulation·Rüdiger von KummerWerner Hacke
Sep 14, 2016·Neurointervention·Duck-Ho GohSam Yeol Ha
Mar 10, 2017·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Adnan I QureshiEmrah Aytac
Jul 15, 2017·Journal of Neurointerventional Surgery·Hisham SalahuddinMouhammad Jumaa
Aug 24, 2017·Stroke; a Journal of Cerebral Circulation·Nils H Mueller-KronastUNKNOWN STRATIS Investigators
Nov 14, 2017·The New England Journal of Medicine·Raul G NogueiraUNKNOWN DAWN Trial Investigators
Jun 20, 2018·Stroke; a Journal of Cerebral Circulation·Jonathan A GrossbergRaul G Nogueira
Sep 7, 2018·World Neurosurgery·Junji UnoHidefuku Gi
Sep 16, 2018·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·R WeberUNKNOWN REVASK investigators
May 23, 2019·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·P BhogalH Henkes
Jun 11, 2019·Stroke; a Journal of Cerebral Circulation·Álvaro García-TornelMarc Ribo
Aug 30, 2019·BMJ : British Medical Journal·Jonathan A C SterneJulian P T Higgins
Jun 2, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Masaya EnomotoTeruyuki Hirano

❮ Previous
Next ❯

Software Mentioned

R
Endnote
Cochrane
Review Manager
STRATIS
metafor
OVID

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.