Subatmospheric pressure wound therapy and the vacuum-assisted closure device: basic science and current clinical successes

Expert Review of Medical Devices
Christina M Plikaitis, Joseph A Molnar

Abstract

This article reviews the development, current theories behind the mechanism of action and clinical use of subatmospheric pressure wound therapy with the vacuum-assisted closure device. An evolving list of indications for subatmospheric pressure therapy is discussed including its use in chronic wounds, traumatic wounds and orthopedic salvage, infected sternal wounds, management of the open abdomen, enterocutaneous fistulae, burn wounds, skin grafts and dermal substitutes, as well as systemic disease processes, such as myoglobinuria. The vacuum-assisted closure device Instill system is also reviewed, in which subatmospheric pressure therapy has been combined with the instillation of therapeutic solutions for the treatment of difficult infected wounds.

References

Sep 1, 1988·Annals of Surgery·D HeimbachG Warden
Feb 1, 1993·Plastic and Reconstructive Surgery·M OleniusM Wickman
Feb 1, 1996·Kidney International·R A Zager
May 26, 1998·Annals of Plastic Surgery·J H BlackburnW P Graham
Sep 12, 1998·Plastic and Reconstructive Surgery·A M SchneiderL C Argenta
Feb 6, 1999·The Journal of Burn Care & Rehabilitation·M J MorykwasL C Argenta
Jan 8, 2000·Plastic and Reconstructive Surgery·J A MolnarM W Marks
Jul 25, 2000·Clinical Orthopaedics and Related Research·J F MooneyA J DeFranzo
Sep 6, 2000·Cells, Tissues, Organs·H G MachensP Mailaender
Mar 27, 2001·Gynecologic Oncology·A A AlvarezG C Rodriguez
Apr 11, 2001·Annals of Plastic Surgery·R E HershD B Drake
Oct 18, 2001·Plastic and Reconstructive Surgery·A J DeFranzoR G Teasdall
Nov 22, 2001·Annals of Plastic Surgery·D N Gwan-Nulla, R S Casal
May 23, 2002·The Journal of Thoracic and Cardiovascular Surgery·Ronny GustafssonRichard Ingemansson
Jul 31, 2002·Archives of Surgery·Lynette A SchererJohn T Owings
Aug 2, 2002·Postgraduate Medical Journal·C CroK R Gardiner
Oct 11, 2002·The Journal of the American Academy of Orthopaedic Surgeons·Lawrence X Webb
Nov 19, 2002·The Journal of Trauma·Preston R MillerMichael C Chang
May 1, 1953·The British Journal of Surgery·D M JACKSON
Sep 23, 2003·Annals of Surgery·T Wright JerniganTiffany K Bee
Dec 17, 2003·The Journal of Trauma·James W SuliburkRao R Ivatury
Apr 3, 2004·Plastic and Reconstructive Surgery·Joseph A MolnarLouis C Argenta
Jul 13, 2004·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine
Jul 24, 2004·Journal of Dental Research·T E DanciuM R Freeman
Oct 1, 2004·Plastic and Reconstructive Surgery·Vishal SaxenaDennis P Orgill

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Citations

Jan 16, 2014·The Indian Journal of Surgery·Tolga AtayVecihi Kirdemir
Jan 18, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Xingang WangChunmao Han
Jul 30, 2014·Advances in Therapy·Dimitrios BaltzisAristidis Veves
Aug 29, 2013·The Spine Journal : Official Journal of the North American Spine Society·Karen J OuseySteve Lui
Feb 13, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Warren Matthew RozenAdel Morsi
May 23, 2008·International Wound Journal·Penny E CampbellJennifer M Smith
Sep 9, 2008·International Wound Journal·UNKNOWN Expert Working Group
May 1, 2008·The British Journal of Surgery·D T UbbinkH Vermeulen
Oct 19, 2013·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Xingang Wang, Chunmao Han
Nov 1, 2012·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Monica C T BloemenEsther Middelkoop
Apr 8, 2015·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Susan M RheeKaren A Robinson
Nov 13, 2012·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Nitin Kumar, Christopher C Thompson
Dec 22, 2010·Advances in Skin & Wound Care·Vasileios I SakellariouPanayiotis J Papagelopoulos
Jun 11, 2015·The Cochrane Database of Systematic Reviews·Debra EvansJo C Dumville
Jan 6, 2021·International Journal of Surgery Case Reports·Veronica L CampanaCarina Giuliani
May 6, 2021·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Carolyn Crumley

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