PMID: 975Nov 14, 1975

Subcellular distribution of phosphatases, proteinases, and ribonucleases in normal human stratum corneum and psoriatic scales

Archives of Dermatological Research
F J FörsterG Leonhardi

Abstract

The subcellular distribution of phosphatases, proteinases, and ribonucleases of normal human stratum corneum and psoriatic scales was determined after differential centrifugation. All psoriatic enzymes showed much increased activities as compared to the normal stratum corneum enzymes. The highest activities of alkaline phosphatase from psoriatic scales could be detected in the nuclear fraction. The main activities of all other tested phosphatases and proteinases were present in the cytoplasmatic fraction. The subcellular distribution of the ribonucleases varied according to the pH value.

References

May 1, 1972·Archives of Dermatology·John J VoorheesE R Harrell
Jul 1, 1972·The Journal of Investigative Dermatology·S L HsiaK M Halprin
Jul 1, 1972·The Journal of Investigative Dermatology·John J VoorheesE R Harrell
Jan 1, 1973·Archives of Dermatology·R K WrightS L Hsia
Jan 1, 1974·Archiv Für Dermatologische Forschung·F J Förster
Jan 1, 1973·The Journal of Investigative Dermatology·P H FleckmanA Z Eisen
Mar 1, 1957·Biochimica Et Biophysica Acta·W I ROGERS, G KALNITSKY
Jun 1, 1960·The Journal of Investigative Dermatology·W FIERS, J DE BERSAQUES

Related Concepts

Alkaline Phosphatase
Cell Nucleus
Protoplasm
Hydrogen-Ion Concentration
Peptide Hydrolases
Phosphoric Monoester Hydrolases
Psoriasis
Alkaline Ribonuclease
Skin
Subcellular Fractions

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