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Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

Dec 18, 2007

W D JohnsonD L McCormick

Abstract

Se-methylselenocysteine (MSC) is an organoselenium compound being developed for breast cancer chemoprevention. To characterize MSC toxicity, CD rats received daily gavage doses of 0, 0.5, 1.0, or 2.0 mg/kg/day (0, 3, 6, or 12 mg/m(2)/day), and beagle dogs received daily gavage doses of ...read more

Mentioned in this Paper

Medina
Metabolic Process, Cellular
Ovarian Diseases
Study
Necrosis
Arrest of Spermatogenesis
Entire Hair Follicle
Thrombocytopenia
Purpura
Hematology (Discipline)
Paper Details
References
  • References21
  • Citations12
123
  • References21
  • Citations12
12

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Subchronic oral toxicity studies of Se-methylselenocysteine, an organoselenium compound for breast cancer prevention

Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association

Dec 18, 2007

W D JohnsonD L McCormick

PMID: 18082924

DOI: 10.1016/j.fct.2007.11.001

Abstract

Se-methylselenocysteine (MSC) is an organoselenium compound being developed for breast cancer chemoprevention. To characterize MSC toxicity, CD rats received daily gavage doses of 0, 0.5, 1.0, or 2.0 mg/kg/day (0, 3, 6, or 12 mg/m(2)/day), and beagle dogs received daily gavage doses of ...read more

Mentioned in this Paper

Medina
Metabolic Process, Cellular
Ovarian Diseases
Study
Necrosis
Arrest of Spermatogenesis
Entire Hair Follicle
Thrombocytopenia
Purpura
Hematology (Discipline)

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Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

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Exocrine glands are a specific type of gland which contains ducts that secrete a specialized substance to a surface, such as the salivary glands, respiratory and gastrointestinal glands. Diseases can affect the exocrine glands and impair their normal functioning. Discover the latest research on exocrine glands here.

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Paper Details
References
  • References21
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  • References21
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