Subclinical atherosclerosis: how and when to treat it?

European Heart Journal Supplements : Journal of the European Society of Cardiology
Laura Gatto, Francesco Prati

Abstract

Atherosclerosis is a condition characterized by a long, initial, asymptomatic phase. Progression of disease could lead to acute coronary events, such as acute myocardial infarction, unstable angina, or sudden cardiac death. However, there are imaging techniques, namely vascular echography and assessment of coronary calcium, capable to make the diagnosis of atherosclerosis at an early stage. There are several studies demonstrating the ability of statins to delay, and in some situation even revert the progression of this condition. Subclinical atherosclerosis is highly prevalent in people with optimal control of the risk factors, and the imaging techniques have been shown to provide an added value over the traditional risk factors: by identifying directly the condition, these techniques allow the reclassification of low-risk to intermediate- or high-risk subjects, thus directing the primary prevention therapeutic strategies, based on high efficacy statins, aimed at delaying or reversing the progression of the disease.

References

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Citations

Feb 11, 2021·Journal of Clinical Medicine·Alyssa L S ChowGary R Small
Mar 7, 2021·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Jovana Kusic MilicevicGordana Dragovic
Jun 19, 2021·Journal of the American College of Cardiology·Sergio Raposeiras-RoubinValentin Fuster
Sep 4, 2021·The American Journal of Clinical Nutrition·Armand ValsesiaLucas Actis-Goretta

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Methods Mentioned

BETA
imaging techniques

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Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

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