Abstract
Clinical heart failure (HF) is associated with CKD and faster rates of kidney function decline. Whether subclinical abnormalities of cardiac structure are associated with faster kidney function decline is not known. The association between cardiac concentricity and kidney function decline was evaluated. This is a longitudinal study of 3866 individuals from the Multi-Ethnic Study of Atherosclerosis (2000-2007) who were free of clinical cardiovascular disease, with an estimated GFR (eGFR) ≥60 ml/min per 1.73 m(2) at baseline and 5 years of follow-up. Concentricity, a measurement of abnormal cardiac size, was assessed by magnetic resonance imaging and evaluated as a continuous measurement and in quartiles. GFR was estimated by creatinine (eGFRcr) and cystatin C (eGFRcys). The association of concentricity with annual eGFR decline, incident CKD, and rapid kidney function decline (>5% per year) was investigated using linear mixed models as well as Poisson and logistic regression, respectively. Analyses adjusted for demographics, BP, diabetes, and inflammatory markers. Median decline was -0.8 (interquartile range, -3.1, -0.5) by eGFRcr. Compared with the lowest quartile of concentricity, persons in the highest quartile had an addition...Continue Reading
References
Mar 15, 1995·Journal of the American College of Cardiology·H M KrumholzD Levy
Apr 1, 1994·Circulation·H IsoT Shimamoto
May 22, 1996·JAMA : the Journal of the American Medical Association·D LevyK K Ho
Jul 13, 1999·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·A LevinO Djurdjev
May 12, 2000·Journal of the American College of Cardiology·J S GottdienerR C Boineau
Oct 25, 2002·American Journal of Epidemiology·Diane E BildRussell P Tracy
Dec 28, 2002·Diabetes Care·UNKNOWN Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
Apr 23, 2003·Journal of the American College of Cardiology·Linda F FriedAnne B Newman
Oct 9, 2003·Kidney International·Nina Vasavada, Rajiv Agarwal
Jun 15, 2004·Journal of the American College of Cardiology·Mark H DraznerDavid S Siscovick
Sep 24, 2004·The New England Journal of Medicine·Alan S GoChi-yuan Hsu
Aug 25, 2005·Coronary Artery Disease·Jonathan C Lyne, Dudley J Pennell
May 23, 2006·AJR. American Journal of Roentgenology·Shunsuke NatoriDavid A Bluemke
Jun 15, 2007·Archives of Internal Medicine·Essam F ElsayedDaniel E Weiner
Feb 26, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Lesley A StevensAndrew S Levey
Oct 11, 2008·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Andrew MoranMichael G Shlipak
Oct 14, 2008·Atherosclerosis·Michael G ShlipakMark J Sarnak
Nov 15, 2008·Journal of the American College of Cardiology·Claudio RoncoRinaldo Bellomo
Dec 6, 2008·Journal of Pharmacological Sciences·Hideyasu KiyomotoAkira Nishiyama
Dec 20, 2008·Journal of the American College of Cardiology·David A BluemkeAaron R Folsom
Jan 10, 2009·American Journal of Epidemiology·Carmen A PeraltaMichael G Shlipak
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Nov 7, 2009·Journal of the American Society of Nephrology : JASN·Michael G ShlipakMark J Sarnak
Dec 3, 2009·American Journal of Epidemiology·Carmen A PeraltaBryan R Kestenbaum
Mar 23, 2011·American Journal of Epidemiology·Daichi ShimboSteven Shea
Oct 8, 2011·Clinical Journal of the American Society of Nephrology : CJASN·Szu-Chia ChenHung-Chun Chen
Citations
Jun 24, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Todd H DriverJoachim H Ix
Apr 29, 2015·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Meyeon Park
Dec 3, 2014·American Heart Journal·Meyeon ParkNisha Bansal
May 23, 2016·The International Journal of Cardiovascular Imaging·Eliel NhamYeon Hyeon Choe
Jul 19, 2017·Heart·Courtney Tuegel, Nisha Bansal
Sep 25, 2017·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Nadine Khouzam, Katherine Wesseling-Perry
Aug 13, 2015·Clinical Journal of the American Society of Nephrology : CJASN·Matthew DenkerUNKNOWN Chronic Renal Insufficiency Cohort Study Investigators
Jan 22, 2015·Clinical Journal of the American Society of Nephrology : CJASN·Nisha BansalMichael Shlipak
Nov 19, 2014·Clinical Journal of the American Society of Nephrology : CJASN·Gates ColbertS Susan Hedayati
Feb 2, 2016·Journal of Hypertension·Ryota YoshitomiTakanari Kitazono
Jan 31, 2020·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Wisit KaewputWisit Cheungpasitporn
Sep 2, 2020·Journal of Nephrology·Giacomo DeferrariEdoardo La Porta
May 18, 2018·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Sahapab AnuwatmateeKwok Leung Ong
Nov 30, 2016·Clinical Hypertension·Carlos R Franco PalaciosBrent Deschaine
Jul 13, 2018·BMC Nephrology·Thomas A MavrakanasDavid M Charytan
Aug 21, 2020·Diabetes Care·Anna BirukovMatthias B Schulze