PMID: 16623260Apr 21, 2006Paper

Subclinical peripheral neuropathy in type 1 diabetic adolescents and its relationship with metabolic control

Srpski arhiv za celokupno lekarstvo
Silvija Sajić, Rada Petrović

Abstract

Professional management of paediatric diabetology, according to consensus guidelines, involves the screening of microvascular complications at puberty. The subclinical form of peripheral neural dysfunction in diabetic teenagers is reported with a frequency of 50-88%, by different authors. The purpose of this study was to evaluate the frequency of subclinical distal neuropathy (DSMN) in type 1 diabetic paediatric patients during the second decade of life, and its relationship with metabolic control. The Endocrinology Department and the Neurology-Physiology Laboratory of the Paediatric Clinic in Belgrade carried out a longitudinal follow-up study (lasting 18 months, beginning in November 2000) on a selection of patients with poor metabolic control. During routine clinical treatment, patients were evaluated using the electrophysiological diagnostic method on peripheral neural dysfunction, a subclinical form of neuropathy. Metabolic control was manifested through HbA1c levels, measured every 3 months, using ion-exchange chromatography. Finally, here is the data collected from the clinical follow-up investigation of 60 children, aged 13-19 (median 15.5 +/- 2.2), with duration of diabetes from 2-16 years (median 6.3 +/- 3.6), and on ...Continue Reading

References

Sep 30, 1993·The New England Journal of Medicine·UNKNOWN Diabetes Control and Complications Trial Research GroupC Siebert
Apr 30, 2002·Hormone Research·Martin Silink
Dec 28, 2002·Diabetes Care·UNKNOWN Expert Committee on the Diagnosis and Classification of Diabetes Mellitus

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Citations

Apr 17, 2012·Diabetes & Metabolism·M LourakiK Karavanaki

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