Subcortical alignment precision in patients with schizophrenia.

Schizophrenia Research
Alan AnticevicDeanna M Barch

Abstract

Previous work has demonstrated less accurate alignment of cortical structures for patients with schizophrenia than for matched control subjects when using affine registration techniques. Such a mismatch presents a potential confound for functional neuroimaging studies conducting between-group comparisons. Critically, the same issues may be present for subcortical structures. However, to date no study has explicitly investigated alignment precision for major subcortical structures in patients with schizophrenia. Thus, to address this question we used methods previously validated for assessment of cortical alignment precision to examine alignment precision of subcortical structures. In contrasts to our results with cortex, we found that major subcortical structures (i.e. amygdala, caudate, hippocampus, pallidum, putamen and thalamus) showed similar alignment precision for schizophrenia (N=48) and control subjects (N=45) regardless of the template used (other individuals with schizophrenia or healthy controls). Taken together, the present results show that, unlike cortex, alignment for six major subcortical structures is not compromised in patients with schizophrenia and as such is unlikely to confound between-group functional neu...Continue Reading

References

Sep 1, 1989·Psychiatry Research·T J CrowD G Owens
Jun 1, 1996·Computers and Biomedical Research, an International Journal·R W Cox
Feb 4, 1998·Journal of Computer Assisted Tomography·R P WoodsJ C Mazziotta
Feb 4, 1998·Journal of Computer Assisted Tomography·R P WoodsJ C Mazziotta
Sep 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·J G CsernanskyM I Miller
Sep 3, 1999·Biological Psychiatry·G D Pearlson, L Marsh
May 2, 2000·The British Journal of Psychiatry : the Journal of Mental Science·T J Crow
Feb 13, 2001·Biological Psychiatry·L C Konick, L Friedman
May 10, 2001·Schizophrenia Research·M E ShentonR W McCarley
May 4, 2004·The American Journal of Psychiatry·John G CsernanskyMichael I Miller
Oct 27, 2004·NeuroImage·Bruce FischlAnders M Dale
Jul 22, 2005·Human Brain Mapping·Brenna D ArgallMichael S Beauchamp
Dec 15, 2005·Progress in Neurobiology·André Aleman, René S Kahn
Oct 31, 2006·Schizophrenia Research·Daniel MamahJohn G Csernansky
Aug 31, 2007·Psychiatry Research·Chihiro NamikiToshiya Murai
Dec 14, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Michael P HarmsJohn G Csernansky
Aug 19, 2008·NeuroImage·John G CsernanskyDavid C Van Essen

❮ Previous
Next ❯

Citations

Mar 19, 2011·Schizophrenia Bulletin·Alan AnticevicDeanna M Barch
Apr 2, 2016·Psychiatry Research. Neuroimaging·Alyson M RichAlan Anticevic
Jul 5, 2013·Cerebral Cortex·Alan AnticevicDavid C Glahn

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.

Antipsychotic Drugs

Antipsychotic drugs are a class of medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia and bipolar disorder. Discover the latest research on antipsychotic drugs here

© 2021 Meta ULC. All rights reserved