Subcutaneous Injection of Nitroglycerin at the Radial Artery Puncture Site Reduces the Risk of Early Radial Artery Occlusion After Transradial Coronary Catheterization: A Randomized, Placebo-Controlled Clinical Trial.

Circulation. Cardiovascular Interventions
Yequn ChenXuerui Tan

Abstract

Transradial coronary catheterization is widely used as a diagnostic or interventional procedure for coronary disease. However, it can lead to adverse complications, such as radial artery occlusion. We sought to determine whether preprocedural injection of nitroglycerin at the radial artery puncture site reduces radial artery occlusion. A total of 188 patients undergoing transradial coronary catheterization were randomized in a single-blind fashion to receive subcutaneous injection of 0.5 mL 0.1% nitroglycerin or a placebo at the radial artery puncture site. The participants underwent ultrasound examinations of the radial artery before and at 24 hours after the procedure. Of the 188 patients enrolled, 182 completed the study, as the procedure failed in 2 participants in the nitroglycerin-treated group and 4 in the placebo group. Baseline demographic and clinical characteristics were similar between 2 groups. Comparing the radial artery diameters before and after the operation, there was a statistically significant increase in the nitroglycerin-treated group (2.48±0.45 versus 2.45±0.46 mm; P=0.003) but a decrease in the placebo control group (2.41±0.50 versus 2.46±0.49 mm; P<0.001). Importantly, the incidence of radial arterial o...Continue Reading

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Citations

Jul 14, 2018·Circulation. Cardiovascular Interventions·Surya Dharma, Ian C Gilchrist
Sep 14, 2019·Circulation. Cardiovascular Interventions·Rajiv Gulati, Mamas A Mamas
Feb 20, 2021·JACC. Cardiovascular Interventions·Guering Eid-LidtJorge Gaspar
Apr 24, 2021·JACC. Cardiovascular Interventions·Gregory A SguegliaStefan Harb
Apr 20, 2021·Anesthesia and Pain Medicine·Sung-Ae ChoJin-Tae Kim
May 8, 2021·JACC. Cardiovascular Interventions·Guering Eid-LidtJorge Gaspar
May 15, 2021·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Sumon RoyIon S Jovin
Aug 18, 2020·Annals of Vascular Surgery·Gérald GahideMathieu Beland
May 30, 2021·Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft·Zygmunt DomagałaMirosław Trzaska

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