Subcutaneous or intramuscular injections of insulin in children. Are we injecting where we think we are?

Diabetes Care
M PolakN Tubiana-Rufi

Abstract

This study was designed to assess the insulin injection location in a group of children who had their injection according to their daily practice, thought to lead to subcutaneous injections. The location of the insulin deposit at the injection site was visualized using an ultrasound device. The exact insulin injection location could be localized, and 18 of 59 injections (30.5%) (one injection for each child) were in the intramuscular tissue. Of the children who had intramuscular injection, 15 of 18 were boys. The children who had an intramuscular injection had a significantly lower percentile of BMI (mean +/- SE: 47 +/- 8 vs. 72 +/- 4, P = 0.004), lower distance from skin surface to muscle fascia without a skinfold (5.6 +/- 0.6 vs. 11 +/- 0.7 mm, P < 0.0001), and a lower distance from skin surface to muscle fascia with a skinfold (8.1 +/- 0.9 vs. 15.9 +/- 0.8 mm, P < 0.0001) than children who had a subcutaneous insulin injection. We identified a group of children at risk for intramuscular insulin injections and that may deserve specific injection technique and advice.

Citations

Oct 12, 2010·Diabetes & Metabolism·A FridUNKNOWN Scientific Advisory Board for the Third Injection Technique Workshop
Sep 13, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·Z MilicevicZ Metelko
Mar 6, 2004·Diabetes Technology & Therapeutics·Niek K ValkBirgitte Berg
Oct 15, 1998·Archives of Disease in Childhood·M G GnanalinghamC P Smith
Aug 26, 2011·Expert Opinion on Drug Delivery·Birtha Hansen, Irina Matytsina
Feb 12, 2013·American Journal of Infection Control·Lisa Black
Sep 6, 2015·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Maria ThomsenRobert Feidenhans'l
Oct 17, 2006·Worldviews on Evidence-based Nursing·Magdalena Annersten, Ania Willman
Sep 24, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·B KargesW Karges
Mar 24, 2006·Journal of Advanced Nursing·Hyunsook Shin, Mi Ja Kim
Nov 29, 2007·Diabetic Medicine : a Journal of the British Diabetic Association·P L HofmanW S Cutfield
Jul 15, 2004·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·R JamalB H Ginsberg
Jun 30, 2010·Diabetes Care·Paul Leslie HofmanWayne Stephen Cutfield
May 24, 2016·SpringerPlus·Sandro GentileUNKNOWN AMD-OSDI Italian Injection Technique Study Group
Sep 7, 2016·Mayo Clinic Proceedings·Anders H FridKenneth W Strauss
Mar 16, 2017·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Sanjay KalraKenneth W Strauss
Sep 23, 2018·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Sanjay KalraKenneth W Strauss
Apr 20, 2016·Current Medical Research and Opinion·Jingyun YuanWeibin Zhou
Aug 31, 2017·Scientific Reports·Hyejeong KimSang Joon Lee

❮ Previous
Next ❯

Related Concepts

Related Feeds

American Diabetes Association Journals

Discover the latest diabetes research published by the journals from the American Diabetes Association.

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.