Subcutaneous versus transvenous implantable defibrillator: An updated meta-analysis.

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Roberto RordorfAlessandro Vicentini

Abstract

Implantable cardioverter-defibrillator (ICD) placement is a well-established therapy for prevention of sudden cardiac death. The subcutaneous implantable cardioverter-defibrillator (S-ICD) was specifically designed to overcome some of the complications related to the transvenous implantable cardioverter-defibrillator (TV-ICD), such as lead complications and systemic infections. Evidence on the comparison of S-ICD vs TV-ICD are limited. The purpose of this study was to conduct an updated meta-analysis comparing S-ICD vs TV-ICD. Electronic databases were searched for studies directly comparing clinical outcomes and complications between S-ICD and TV-ICD. The primary outcome was the composite of clinically relevant complications (lead, pocket, major procedural complications; device-related infections) and inappropriate shocks. Secondary outcomes included death and the individual components of the primary outcome. Thirteen studies comprising 9073 patients were included in the analysis. Mean left ventricular ejection fraction was 40% ± 10%; 30% of patients were female; and 73% had an ICD implanted for primary prevention. There was no statistically significant difference in the risk of the primary outcome between S-ICD and TV-ICD (od...Continue Reading

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Citations

Jun 24, 2021·Annals of Medicine and Surgery·Muhammad Arslan CheemaDonald Haas
Jul 17, 2021·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Alessio GasperettiMauro Biffi
Sep 10, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Giulio ConteAngelo Auricchio
Nov 20, 2021·Journal of Cardiovascular Electrophysiology·Samuel F SearsRajasekhar Nekkanti

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