Subependymal Giant Cell Astrocytoma Presenting with Tumoral Bleeding: A Case Report

Brain Tumor Research and Treatment
Jae-Young KimSeul-Kee Kim

Abstract

We report a rare case of subependymal giant cell astrocytoma (SEGA) associated with tumoral bleeding in a pediatric patient without tuberous sclerosis complex (TSC). A 10-year-old girl presented with a 2-week history of an increasingly aggravating headache. Brain magnetic resonance imaging revealed an approximately 3.6-cm, well-defined, heterogeneously enhancing mass with multistage hemorrhages on the right-sided foramen of Monro. The tumor was completely resected using a transcallosal approach. Intraoperatively, the mass presented as a gray-colored firm tumor associated with acute and subacute hemorrhages. The origin of the mass was identified as the ventricular septum adjacent to the foramen of Monro. A pathological analysis revealed pleomorphic multinucleated eosinophilic tumor cells with abundant cytoplasm. These cells showed positive staining for the glial fibrillary acidic protein and S100 protein. A diagnosis of SEGA was established. The patient recovered without any neurological symptoms. There was no evidence of TSC. The radiological follow-up showed no recurrence for 2 years. This was a case of SEGA with intratumoral hemorrhage, for which a favorable outcome was achieved, without any neurological deficit after tumoral...Continue Reading

References

Dec 1, 1991·Arquivos de neuro-psiquiatria·L M Barbosa-CoutinhoN P Ferreira
Feb 1, 1989·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S FujiwaraS Nishio
Jan 1, 1995·Pediatric Radiology·P KalinaR A Hyman
Sep 1, 1994·Arquivos de neuro-psiquiatria·O HamamotoL Souza-Queiróz
Jan 1, 1994·Pediatric Neurosurgery·G SinsonL Schut
Nov 14, 1997·Surgical Neurology·Y G ParkS S Chung
Mar 4, 1999·The New England Journal of Medicine·J KwiatkowskaD J Kwiatkowski
Aug 25, 2001·Journal of Neuro-oncology·S K KimJ G Chi
Nov 26, 2004·Journal of Child Neurology·Kit-Sing AuHope Northrup
Feb 3, 2006·Annals of Neurology·David Neal FranzKerry R Crone
Jan 18, 2007·Neurosurgery·Sandrine de RibaupierreOlivier Delalande
Apr 9, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·P StavrinouP Selviaridis
Feb 25, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M E A P M AdriaensenM Prokop
Mar 27, 2009·Stereotactic and Functional Neurosurgery·Mark A HendersonThomas C Witt
Oct 19, 2010·Journal of Neurosurgery·Kyung-Jae ParkL Dade Lunsford
Nov 5, 2010·The New England Journal of Medicine·Darcy A KruegerDavid Neal Franz
May 9, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Thomas L BeaumontMatthew D Smyth
Nov 10, 2012·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Hugo StermanManoel Jacobsen Teixeira
Feb 19, 2013·Journal of Neurosurgery. Pediatrics·Hideki Ogiwara, Nobuhito Morota
Sep 24, 2013·Pediatric Neurology·Hope NorthrupUNKNOWN International Tuberous Sclerosis Complex Consensus Group
May 16, 2015·Brain Tumor Research and Treatment·Tae-Young JungKyung-Hwa Lee
May 16, 2015·Journal of Neurosurgery. Pediatrics·Thomas L BeaumontMatthew D Smyth

❮ Previous
Next ❯

Citations

Jun 30, 2019·Acta neurologica Belgica·Jessica Vanhaebost, Julie Lelotte
Jul 10, 2020·Pediatric Radiology·Fabricio Guimarães GonçalvesArastoo Vossough
Jul 30, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mario SuzukiHajime Arai
Jan 6, 2021·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Viera KútnaSaak V Ovsepian
Mar 6, 2021·Neuro-oncology Practice·James S RyooAnkit I Mehta
Nov 7, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Tsuyoshi SasakiTakeo Goto

❮ Previous
Next ❯

Methods Mentioned

BETA
surgical resection

Related Concepts

Related Feeds

Astrocytes

Astrocytes are glial cells that support the blood-brain barrier, facilitate neurotransmission, provide nutrients to neurons, and help repair damaged nervous tissues. Here is the latest research.