Subepithelial corneal amyloid deposits in a case of congenital glaucoma: a case report

Cornea
Geeta Kashyap Vemuganti, Anil K Mandal

Abstract

To report a rare association of subepithelial amyloid deposits in a long-standing case of congenital glaucoma. A 5-year-old girl was brought to the emergency service with complaints of bleeding from the left eye after injury to the eye with the door handle. Parents gave history of enlarged black portion of the eye since birth with increasing white opacity from the age of 6 months. On examination under general anesthesia, the left eye showed a limbal tear extending from 7 to 3.30 o'clock position and uveal prolapse. The right eye showed corneal edema, megalocornea, central white raised plaque, and high intraocular pressure. A diagnosis of bilateral congenital glaucoma with open globe injury, left eye, corneal scarring with degeneration, right eye was made and was advised enucleation. The enucleated eye was submitted for routine histologic examination. At a 3-year follow-up, there was an increase in the corneal scarring, with no significant improvement in vision. The child refused keratoplasty and was referred to low vision centre for visual rehabilitation. The enucleated eye was distorted and filled with blood. The cornea showed confluent pink homogenous wavy deposits in the subepithelial region. These deposits appeared brick re...Continue Reading

References

Feb 1, 1991·Ophthalmology·C S MattaA A al-Rajhi
Jan 1, 1988·Ophthalmology·G A SternC I Hood
Jan 1, 1980·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·J François

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Citations

Apr 7, 2007·Cornea·Tsung-Jen WangYu-Chih Hou
Jan 22, 2010·Journal of Genetics·Kunal Ray, Suddhasil Mookherjee
Mar 5, 2013·Ophthalmology·Kaoru Araki-SasakiShigeru Kinoshita
Oct 8, 2009·Brain Research Bulletin·Alexei Surguchev, Andrei Surguchov
Feb 3, 2015·Muscle & Nerve·Thomas J WaltersBenjamin T Corona

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