Subfoveal Choroidal Thickness in Eyes with Neovascular Age-Related Macular Degeneration Treated with Anti-Vascular Endothelial Growth Factor Agents

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Tereza Cristina Moreira KanadaniMárcio Bittar Nehemy

Abstract

We aimed to assess the subfoveal choroidal thickness (SFChT) and the effect of treatment with anti-vascular endothelial growth factor (anti-VEGF) agents on the SFChT in age-related macular degeneration (AMD) subtypes. We enrolled 128 eyes of 107 patients with neovascular AMD (60 women; 47 men; mean age, 73.6 ± 8.9 years), and prospectively evaluated the best-corrected visual acuity (BCVA) and SFChT at baseline and at 3, 6, and 12 months after treatment with anti-VEGF agents. Patients were assigned to the typical AMD, polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP) subgroups. In total, 85 (66.4%), 31 (24.2%), and 12 (9.4%) eyes were assigned to the typical AMD, PCV, and RAP subgroups, respectively. The baseline mean BCVA was 0.75 ± 0.26, 0.72 ± 0.21, and 0.77 ± 0.24 logMAR in the typical AMD, PCV, and RAP subgroups, respectively (p = 0.774). The mean baseline SFChT was 203.20 ± 35.80, 271.80 ± 24.50, and 182.93 ± 31.31 µm, respectively (p < 0.001). Mean SFChT significantly decreased from baseline to 3, 6, and 12 months after treatment. The RAP subtype presented a significantly higher decrease in SFChT compared to the other subtypes (p = 0.01). The percentage reduction in SFChT was not signifi...Continue Reading

References

Apr 1, 1997·Archives of Ophthalmology·L A YannuzziD A Orlock
Dec 31, 1997·American Journal of Ophthalmology·E Friedman
Jan 8, 2003·Ophthalmology Clinics of North America·Antonio P CiardellaLawrence A Yannuzzi
Mar 12, 2004·American Journal of Ophthalmology·Ronald KleinMylan R Vannewkirk
Mar 12, 2004·American Journal of Ophthalmology·Hans E Grossniklaus, W Richard Green
Feb 4, 2005·Retina·Anthony P Adamis, David T Shima
May 19, 2007·American Journal of Ophthalmology·Ichiro MarukoKuniharu Saito
Jun 21, 2008·Investigative Ophthalmology & Visual Science·Sandra LiakopoulosSrinivas R Sadda
Jul 22, 2008·American Journal of Ophthalmology·Richard F SpaideMaria C Pozonni
Jan 29, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hideki KoizumiShigeru Kinoshita
Jun 16, 2012·Clinical Ophthalmology·Abdallah A EllabbanNagahisa Yoshimura
Nov 20, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Waheeda RahmanLyndon da Cruz
Nov 28, 2013·Investigative Ophthalmology & Visual Science·Florence CoscasEric H Souied
Jan 11, 2014·Retina·Taizo YamazakiShigeru Kinoshita
Feb 13, 2014·Investigative Ophthalmology & Visual Science·Elliott H SohnRobert F Mullins
Jul 3, 2015·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Magda GharbiyaVittorio Cacace
Sep 24, 2015·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Frederico Braga PereiraMárcio B Nehemy
Jan 9, 2016·American Journal of Ophthalmology·Daniel Shu Wei TingChui Ming Gemmy Cheung
Jan 20, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Cheolmin YunKuhl Huh

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