PMID: 9175937May 1, 1997Paper

Subgroups of primary Sjögren's syndrome. Sjögren's syndrome in male and paediatric Greek patients

Annals of the Rheumatic Diseases
A A DrososA Siamopoulou-Mavridou

Abstract

To describe the clinical and serological findings in male and paediatric Sjögren's syndrome (SS) patients. Using the European criteria for the diagnosis of SS 12 male and 13 paediatric patients were identified and compared with those of 30 consecutive unselected adult female SS patients. The mean (SD) age of paediatric patients was 9.4 (2.2) years, ranging from 6 to 14 years. Recurrent parotid gland enlargement was the initial clinical manifestation in the majority of the children with a statistical significance compared with male (p < 0.01) and with female patients (p < 0.0001). Sicca manifestations were the most common clinical symptoms in male and female patients at disease onset. The systemic manifestations were similar among the three groups except that men showed lower frequency of arthritis (p < 0.05) and Raynaud's phenomenon (p < 0.05) compared with women. No differences were found among the immunological profile of children and female patients, while male patients had a lower frequency of antinuclear antibodies (p < 0.025) and antibodies to Ro(SSA) nuclear antigens (p < 0.025) compared with women. Primary SS is rare in children and men in Greece. Recurrent parotid gland enlargement is the most common clinical finding a...Continue Reading

Citations

Sep 5, 2002·Arthritis and Rheumatism·Daniel H SolomonUNKNOWN American College of Rheumatology Ad Hoc Committee on Immunologic Testing Guidelines
Dec 17, 2009·Zeitschrift für Rheumatologie·G Westhoff, A Zink
Dec 24, 2011·Autoimmune Diseases·Manuel J Amador-PatarroyoGladis Montoya-Ortiz
May 18, 2007·Clinical Pediatrics·Mahmut CivilibalNil Arisoy
Nov 5, 2015·Biology of Sex Differences·Jessica E BrandtDeLisa Fairweather
Jul 10, 2008·Scandinavian Journal of Rheumatology·G GondranE Vidal
Jul 22, 2015·Iranian Journal of Pediatrics·K Jagadish KumarH V Sowmya
Sep 13, 2020·International Journal of Rheumatic Diseases·Youngjae ParkSeung-Ki Kwok
May 17, 2017·Biology of Sex Differences·Jorge I Ramírez SepúlvedaMarie Wahren-Herlenius
Aug 4, 1999·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·T SaitoH Fukuda
Jul 25, 2017·Clinical Rheumatology·Simrun VirdeeCoziana Ciurtin
Aug 15, 1998·Dermatologic Clinics·T N DeSilva, D W Kress

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.