Subretinal hemorrhages associated with age-related macular degeneration in patients receiving anticoagulation or antiplatelet therapy

American Journal of Ophthalmology
Claudia Kuhli-HattenbachL O Hattenbach

Abstract

To evaluate the incidence of and risk factors for subretinal hemorrhages in age-related macular degeneration (AMD) patients on anticoagulation or antiplatelet therapy. Retrospective, observational case series. We retrospectively reviewed the medical and photographic records of 71 consecutive patients who sought treatment at our institution with acute subretinal hemorrhages complicating age-related macular degeneration. The size of the subretinal hemorrhage was measured in standardized Macular Photocoagulation Study disc areas. Data on the use of medications and medical indications for anticoagulation and antiplatelet therapy were obtained. Overall, patients receiving antithrombotic therapy had a significantly larger subretinal hemorrhage size (mean, 9.71 disc areas) than patients not receiving anticoagulant or antiplatelet therapy (mean, 2.99 disc areas). Subgroup analysis revealed that both antiplatelet (P < .0001) and anticoagulant therapy (P = .003) were associated with a significantly larger bleeding size. Moreover, subgroup analysis among patients with arterial hypertension revealed that individuals receiving antithrombotic therapy had a statistically significantly larger hemorrhage size than hypertensive patients who did ...Continue Reading

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Citations

Jul 21, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·C Kuhli-HattenbachL-O Hattenbach
Jul 4, 2012·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·U Ritzau-TondrowH Hoerauf
May 29, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Chui Ming Gemmy CheungTien Yin Wong
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Oct 14, 2014·Ophthalmology·Michael M AltaweelUNKNOWN Comparison of Age-related Macular Degeneration Treatments Trials CATT Research Group
May 26, 2011·Seminars in Ophthalmology·Ayham R Skaf, Tahmer Mahmoud
Oct 23, 2016·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Yoo-Ri ChungKihwang Lee
Nov 8, 2015·Ophthalmology·Gui-Shuang YingUNKNOWN Comparison of Age-Related Macular Degeneration Treatments Trials Research Group
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Oct 10, 2021·American Journal of Ophthalmology·Alexander MehtaUNKNOWN IVAN Study Investigators

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