Subspecialization of R2R3-MYB Repressors for Anthocyanin and Proanthocyanidin Regulation in Forage Legumes

Frontiers in Plant Science
Nick W Albert

Abstract

The synthesis of anthocyanin pigments and proanthocyanidins (condensed tannins) is regulated by MYB-bHLH-WDR (MBW) transcription factor complexes in all angiosperms studied to date. Tr-MYB133 and Tr-MYB134 were isolated from Trifolium repens and encode R2R3-MYBs that antagonize the activity of MBW activation complexes. These two genes are conserved in other legume species, and form two sub-clades within the larger anthocyanin/proanthocyanidin clade of MYB repressors. However, unlike petunia and Arabidopsis, these R2R3-MYB repressors do not prevent ectopic accumulation of anthocyanins or proanthocyanidins. Instead, they are expressed when anthocyanins or proanthocyanidins are being synthesized, and provide feedback regulation to MBW complexes. This feedback occurs because Tr-MYB133 and Tr-MYB134 are themselves regulated by MBW complexes. Tr-MYB133 is regulated by MBW complexes containing anthocyanin-related R2R3-MYB proteins (Tr-RED LEAF), while Tr-MYB134 is regulated by complexes containing the proanthocyanidin R2R3-MYBs (Tr-MYB14). Other features of the MBW gene regulation networks are also conserved within legumes, including the ability for the anthocyanin MBW complexes to activate the expression of the AN1/TT8 clade bHLH fac...Continue Reading

References

Nov 28, 2001·The Plant Journal : for Cell and Molecular Biology·A AharoniA P O'Connell
Jul 17, 2004·The Plant Journal : for Cell and Molecular Biology·Antoine BaudryLoïc Lepiniec
Sep 14, 2004·The Plant Journal : for Cell and Molecular Biology·Ilona M ZimmermannJoachim F Uhrig
Dec 4, 2004·Journal of Biomedicine & Biotechnology·Kevin S Gould
Feb 15, 2005·Trends in Plant Science·Nicola A Ramsay, Beverley J Glover
Feb 22, 2005·The New Phytologist·Richard A DixonShashi B Sharma
May 11, 2005·Trends in Plant Science·Ronald KoesFrancesca Quattrocchio
Sep 20, 2005·The Plant Journal : for Cell and Molecular Biology·Shashi B Sharma, Richard A Dixon
May 1, 2007·Journal of Animal Science·K A BeaucheminT A McAllister
Jun 6, 2008·The Plant Journal : for Cell and Molecular Biology·Kyoko MatsuiMasaru Ohme-Takagi
Jun 6, 2008·The Plant Journal : for Cell and Molecular Biology·Christian DubosLoïc Lepiniec
Apr 17, 2009·The Plant Journal : for Cell and Molecular Biology·Gregory J PeelRichard A Dixon
Apr 22, 2009·Journal of Experimental Botany·Nick W AlbertKevin M Davies
Apr 15, 2010·Plant Physiology·Jian ZhaoRichard A Dixon
Oct 16, 2010·PloS One·Roger P HellensT H Noel Ellis
Mar 1, 2011·Phytochemistry·Raymond V Barbehenn, C Peter Constabel
May 19, 2011·The Plant Cell·Cathie MartinChiara Tonelli
Dec 15, 2011·Plant Physiology·Shamila Weerakoon AbeynayakeGerman Spangenberg
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jerome VerdierMichael K Udvardi
Aug 21, 2012·Current Opinion in Biotechnology·Richard A DixonJi Hyung Jun
Nov 8, 2012·Plant Biotechnology Journal·Richard V EspleyAndrew C Allan

❮ Previous
Next ❯

Citations

Jul 5, 2016·Frontiers in Plant Science·Sangam L DwivediRodomiro Ortiz
May 31, 2019·Journal of Experimental Botany·Varsha TirumalaiPadubidri V Shivaprasad
Feb 28, 2020·International Journal of Molecular Sciences·Linyan SongLingfei Xu
Jan 9, 2019·Frontiers in Plant Science·Nicola BonarCsaba Hornyik
Nov 30, 2019·Scientific Reports·Blue J PlunkettAndrew C Allan
Jul 14, 2016·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Darren Chern Jan WongJosé Tomás Matus
Apr 7, 2021·Developmental Cell·Camila B Lopez-AnidoDominique C Bergmann
Jun 27, 2019·Journal of Agricultural and Food Chemistry·Marissa B RoldanChristine R Voisey

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
RNA-seq
transgenic

Software Mentioned

MUSCLE
Genstat
Geneious

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.