Substance P and Calcitonin gene-related peptide expression in human periodontal ligament after root canal preparation with Reciproc Blue, WaveOne Gold, XP EndoShaper and hand files

International Endodontic Journal
Javier Caviedes-BucheliHugo Roberto Munoz

Abstract

To quantify Substance P (SP) and Calcitonin gene-related peptide (CGRP) expression in healthy human periodontal ligament from premolars after root canal preparation with Reciproc Blue, WaveOne Gold, XP EndoShaper and hand files. A total of 50 human periodontal ligament samples were obtained from healthy mandibular premolars where extraction was indicated for orthodontic reasons. Prior to extraction, 40 of these premolars were equally divided into four groups, and root canals were prepared using four different systems: Reciproc Blue, WaveOne Gold, XP EndoShaper and a hand instrumentation technique. The remaining 10 healthy premolars were extracted without treatment and served as a negative control group. All periodontal ligament samples were processed, and SP and CGRP were measured by radioimmunoassay. The Kruskal-Wallis test was used to establish significant differences between groups and LSD post hoc comparisons were also performed. Greater SP and CGRP values were found in the hand instrumentation group, followed by the XP EndoShaper, WaveOne Gold and the Reciproc groups. The lower SP and CGRP values were for the healthy periodontal ligament group. The Kruskal-Wallis test revealed significant differences between groups (P < 0....Continue Reading

References

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Nov 26, 2008·Journal of Endodontics·Javier Caviedes-BucheliHugo Roberto Muñoz
May 5, 2009·Journal of Endodontics·Javier Caviedes-BucheliHugo Roberto Muñoz
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Jan 31, 2017·Journal of Endodontics·Gustavo De-DeusNicola Maria Grande
Jun 3, 2017·International Journal of Epidemiology·Venexia M WalkerRichard M Martin

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Citations

Nov 22, 2020·Australian Endodontic Journal : the Journal of the Australian Society of Endodontology Inc·Thomas Gerhard WolfBenjamín Briseño-Marroquín
Jun 26, 2021·Journal of Endodontics·Felipe XavierDiana de Albuquerque

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