PMID: 6164582Dec 1, 1980Paper

Substance P in human cord blood and its degradation by placenta in vitro

European Journal of Obstetrics, Gynecology, and Reproductive Biology
P SkrabanekD Powell

Abstract

Plasma immunoreactive substance P (iSP) was measured by radioimmunoassay in 12 paired samples of maternal and cord blood, and in placental extracts. The mean plasma iSP concentration in the cord vein was 42.5 pg/ml, as compared to 77.3 pg/ml in the maternal peripheral vein plasma. There was no difference in the mean iSP concentration in the cord vein and artery. Although no iSP was detected in placental tissue, the placenta could not be excluded as the source of iSP in cord blood in view of the rapid degradation of synthetic SP by the placental in vitro.

References

Sep 1, 1979·Neuroscience Letters·E G NcGeer, E A Singh
Mar 1, 1979·The Journal of Clinical Endocrinology and Metabolism·G ShambaughJ F Wilber
Sep 3, 1979·Life Sciences·K CsontosH J Teschemacher
Jan 1, 1978·Neuroscience·P AlmF Sundler
Jul 27, 1979·Brain Research·R F Gilbert, P C Emson
Jul 1, 1979·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·D CusackD Powell
Jul 20, 1979·Naunyn-Schmiedeberg's Archives of Pharmacology·D E CannonD Powell
May 11, 1978·Nature·D ClarkH Bowers
Dec 1, 1976·Irish Journal of Medical Science·R O'ConnellD Powell
Jul 21, 1971·Nature: New Biology·M M ChangH D Niall
May 1, 1980·The Journal of Clinical Endocrinology and Metabolism·W B Watkins, S S Yen
Jan 18, 1980·Science·G S Khodr, T M Siler-Khodr
Jan 4, 1980·Science·J C HouckH I Yamamura
Feb 1, 1980·Medical Hypotheses·P Skrabanek, D Powell

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