Substantia nigra MR imaging signal changes and cardiomyopathy following prenatal exposure to cocaine and heroin.

AJNR. American Journal of Neuroradiology
R ArnoldG Gaisie

Abstract

Exposure to cocaine in utero results in behavioral and neurodevelopmental abnormalities that persist into adulthood. Conventional MR imaging has generally failed to reveal the expected structural lesions to explain these clinical findings. We report a case of focal MR imaging signal-intensity changes in the substantia nigra, locus ceruleus, and other selected nerve tracts and nuclei in a child exposed prenatally to cocaine and other drugs. The patient also had dilated cardiomyopathy.

References

Nov 1, 1994·Archives of Pediatrics & Adolescent Medicine·J J FrassicaS E Lipshultz
Jul 1, 1994·Journal of Computer Assisted Tomography·B Gomez-Anson, R G Ramsey
Jan 27, 2004·Brain Research. Developmental Brain Research·Michael S Lidow

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Citations

Apr 10, 2013·Neuroscience and Biobehavioral Reviews·Daniel KofinkMartien J Kas

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