PMID: 20645570Jul 22, 2010Paper

Substantiating the mechanism of action of modified laser cyclocoagulation

Vestnik oftalmologii
A E EgorovD V Kats

Abstract

The authors studied in an experiment the processes of a limited and controlled inflammatory reaction after modified laser cyclocoagulation (MLCC) and estimated the content of adenosine triphosphate (ATP) and guanosine triphosphate (GTP) in the retina and optic nerve. Hypotensive and trophic MLCC were carried out in 36 grey Shinshilla rabbits (36 eyes) by the standard procedure. Thirty-six pair eyes without MLCC served as a control. Biochemical studies yielded estimates of changes in the content of ATP and GTP in the hypotensive and trophic MLCC and control groups. The experiment showed an increase in the levels of ATP and GTP in nmole. The performed experimental studies proved that ocular exchange processes became activated and the content of ATP and GTP increased.

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