Substrate-energy metabolism and metabolic risk factors for cardiovascular disease in relation to fetal growth and adult body composition

American Journal of Physiology. Endocrinology and Metabolism
Osama A KensaraHertfordshire Study Group

Abstract

The effect of fetal programming on intermediary metabolism is uncertain. Therefore, we examined whether fetal programming affects oxidative and nonoxidative macronutrient metabolism and the prevalence of the metabolic syndrome in adult life. Healthy older men, aged 64-72 years, with either a lower birth weight (LBW, <or=25th %ile; n = 16) or higher birth weight (HBW, >or=75th %ile; n = 13) had measurements of 1) net oxidative metabolism using indirect calorimetry before and for 6 h after a mixed meal (3,720 kJ) and 2) postprandial oxidation of exogenous [13C]palmitic acid. Body composition was measured using dual-energy X-ray absorptiometry. After adjustment for current weight and height, the LBW group had a lower resting energy expenditure (REE) in the preprandial (4.01 vs. 4.54 kJ/min, P = 0.015) and postprandial state (4.60 vs. 5.20 kJ/min, P = 0.004), and less fat-free mass than the HBW group. The BW category was a significant, independent, and better predictor of REE than weight plus height. There were no significant differences between groups in net oxidative and nonoxidative macronutrient (protein, fat, carbohydrate) metabolism (or of exogenous [13C]palmitate) or in the prevalence of the metabolic syndrome, which was pre...Continue Reading

References

Oct 1, 1992·The American Journal of Physiology·M EliaP R Murgatroyd
Oct 26, 1991·BMJ : British Medical Journal·C N HalesP D Winter
Jan 1, 1990·Metabolism: Clinical and Experimental·J A WeststrateJ G Hautvast
Feb 25, 1988·The New England Journal of Medicine·E RavussinC Bogardus
Aug 1, 1995·Diabetic Medicine : a Journal of the British Diabetic Association·D I Phillips
Dec 1, 1994·Journal of the American College of Nutrition·P A TataranniE Ravussin
Mar 1, 1996·Annals of Human Biology·N J FullerM Elia
Dec 1, 1996·Archives of Disease in Childhood·J W MatthesJ A Bethel
Jun 1, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·D B AllisonS B Heymsfield
Nov 22, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·T RiceC Bouchard
Apr 8, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E Ravussin, J F Gautier
Sep 13, 2001·Diabetic Medicine : a Journal of the British Diabetic Association·T HarderA Plagemann
Oct 24, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·R J LoosR Vlietinck
Apr 25, 2002·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·J ErikssonD Barker
Jun 25, 2002·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·Y-W ParkD Gallagher
Jul 30, 2002·The American Journal of Clinical Nutrition·Jaehee KimDympna Gallagher
Apr 4, 2003·Journal of Physiological Anthropology and Applied Human Science·Tomohiro OkuraHiroshi Shimokata
May 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·C A NewsomeC M Law
Jun 25, 2003·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·I Rogers, UNKNOWN EURO-BLCS Study Group
Aug 15, 2003·Obesity Research·Roland L WeinsierBetty E Darnell
Jun 24, 2004·The American Journal of Clinical Nutrition·Avan Aihie SayerDavid I Phillips
Feb 12, 2005·The Journal of Physiology·I Caroline McMillenBeverly S Mühlhäusler
Jun 22, 2005·Clinical Science·Roselle L CrippsSusan E Ozanne

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Citations

Apr 20, 2013·The British Journal of Nutrition·Mia-Maria PeräläJohan G Eriksson
Jan 18, 2013·European Journal of Clinical Nutrition·A A JacksonS Wootton
Jul 27, 2012·Metabolic Syndrome and Related Disorders·Emily W HarvilleGerald S Berenson
Oct 16, 2009·Journal of the Royal Society, Interface·Mathieu Cloutier, Peter Wellstead
Jan 1, 2010·Journal of Nutrigenetics and Nutrigenomics·Alan A JacksonKaren A Lillicrop
Apr 18, 2007·BMC Evolutionary Biology·Milind G Watve, Chittaranjan S Yajnik
Sep 10, 2011·PloS One·Mia-Maria PeräläJohan G Eriksson
Feb 19, 2008·Best Practice & Research. Clinical Endocrinology & Metabolism·Abdul G Dulloo
Dec 25, 2007·Physiology & Behavior·E C Cottrell, S E Ozanne
Jul 21, 2011·Journal of Obesity·Ulfat BaigMaithili Jog
Jun 3, 2015·Wiley Interdisciplinary Reviews. Systems Biology and Medicine·Pramod R SomvanshiK V Venkatesh
Mar 1, 2011·Annals of Medicine·Samuel SandbogeJohan G Eriksson
May 23, 2015·Journal of Developmental Origins of Health and Disease·S-K LeeD J Hoffman
Dec 9, 2016·Annals of Human Biology·Daniel J HoffmanColleen M Doak
Mar 22, 2018·European Journal of Clinical Nutrition·Abdul G DullooYves Schutz
Nov 30, 2006·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A G DullooJ-P Montani
Jul 20, 2007·American Journal of Human Biology : the Official Journal of the Human Biology Council·Christopher W Kuzawa
Jul 10, 2013·Neonatal Network : NN·Sharon Anderson, Susan Sklower Brooks
May 24, 2012·Current Opinion in Lipidology·Mia-Maria Perälä, Johan G Eriksson
Oct 25, 2007·Biochemical Society Transactions·R L CrippsS E Ozanne
Nov 9, 2018·European Journal of Clinical Nutrition·Meghan K ShirleyJonathan C K Wells
Dec 1, 2017·Nutrition Reviews·Daniel J HoffmanDaniel B Hardy
Jul 7, 2011·Journal of the American College of Nutrition·Francisco B OrtegaIdoia Labayen
Jan 29, 2019·Maternal & Child Nutrition·Victor O OwinoAlan A Jackson
Dec 4, 2020·Physiological Reviews·Daniel J HoffmanDaniel B Hardy
Feb 6, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Abdul G Dulloo

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