Subthalamotomy in cervical dystonia: A case study of lesion location and clinical outcome

Movement Disorders : Official Journal of the Movement Disorder Society
Christian K E MollA Münchau

Abstract

Here we report a 63-year-old woman with primary cervical dystonia (CD) whose symptoms subsided for more than 30 years following a unilateral stereotactic subthalamotomy contralateral to the overactive left sternocleidomastoid muscle but then gradually recurred over a period of several months. The aim of the present study was to correlate the topography of the stereotactic lesion with the long lasting therapeutic effect. High-resolution magnetic resonance imaging and subsequent stereotactic analysis were performed to determine the anatomical localization of the lesion. The primary coagulation focus comprised the posterior subthalamic white matter in the prelemniscal radiation and field H of Forel. Neighboring structures were implicated to various extents. It is suggested that the posterior subthalamic area, with its abundance of interconnecting fibers and related nuclei, represents an effective target for the neurosurgical treatment of CD that may be explored further with deep brain stimulation.

References

Jan 1, 1972·Confinia Neurologica·F MundingerJ Disselhoff
Feb 1, 1996·Journal of Neurophysiology·T KokkoroyannisA K Moschovakis
Feb 16, 2002·Science·Eliana M KlierJ Douglas Crawford
Jan 1, 1954·Archiv für Psychiatrie und Nervenkrankheiten, vereinigt mit Zeitschrift für die gesamte Neurologie und Psychiatrie·R HASSLER, W R HESS
May 7, 1964·The New England Journal of Medicine·I S COOPER
Oct 1, 1963·Journal of Neurosurgery·O J ANDYF R SIAS
Oct 1, 1963·Journal of Neurosurgery·E A SPIEGELH W BAIRD
Mar 10, 2004·Stereotactic and Functional Neurosurgery·Thomas J LoherJoachim K Krauss
Nov 10, 2004·Journal of Digital Imaging·Antoine RossetOsman Ratib
Dec 8, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Kelvin L ChouGordon H Baltuch
Jan 11, 2005·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Richard G BittarTipu Z Aziz

❮ Previous
Next ❯

Citations

Jun 12, 2009·Current Neurology and Neuroscience Reports·Vicki Shanker, Susan B Bressman
Jan 1, 2010·Neuromodulation : Journal of the International Neuromodulation Society·Peter A Pahapill, Barbara O'Connell
Jul 12, 2012·Therapeutic Advances in Neurological Disorders·Cathérine C S Delnooz, Bart P C van de Warrenburg
Jun 27, 2009·Neurologic Clinics·Cordelia S Schwarz, Susan B Bressman

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.