Subtotal parathyroidectomy versus total parathyroidectomy with autotransplant in secondary hyperparathyroidism — a single-centre prospective cohort of 43 patients

Endokrynologia Polska
Radu Mircea NeagoeDaniela Tatiana Sala

Abstract

The need for parathyroidectomy remains high in the group of patients on long-term dialysis with medically refractory secondary hyperparathyroidism (sHPT). We aim to compare the results after subtotal parathyroidectomies (sPtx) and total parathyroidectomies with autotransplant (tPtx + AT) performed for sHPT at a single referral centre. This prospective study comparatively analysed sPtx and tPtx + AT performed in our department between February 2010 and December 2014. We followed-up both surgical techniques, with respect to the main clinical symptoms, laboratory data, mortality, and recurrent disease. Forty-three patients on whom we performed 26 sPtx and 19 tPtx + AT were entered in the study. There were no statistically significant differences between groups as far as demographic and preoperative clinical data are concerned. We did not encounter postoperative mortality in either of the groups. The follow-up period was significantly longer for the sPtx group (p = 0.04). The immediate postoperative serum calcium levels were significantly lower in the tPtx + AT group (p = 0.009). Definitive hypoparathyroidism was encountered in two patients in the sPtx group (8.3%) and in one from the tPtx + AT group (5.26%). Four patients from the...Continue Reading

Citations

Feb 16, 2019·The Journal of Critical Care Medicine·Tatiana Daniela SalaIonela Paşcanu
Jan 10, 2020·The Journal of Critical Care Medicine·Corina Pop RaduDaniela Tatiana Sala
Jun 5, 2019·The Journal of Critical Care Medicine·Mircea MureșanArpad Torok

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