Oct 1, 1977

Subtype characteristics of the surface antigen of hepatitis B in different regions of the USSR

Zhurnal mikrobiologii, epidemiologii, i immunobiologii
S A GrannikovaT M Lorinskaia


A method of preparation of subtypical antisera to two determinants of hepatitis B surface antigen (anti-HBs Ag/ay and anti-HBs Ag/ad) is described. The test system obtained was approbated on 1400 antigen-positive sera collected from blood donors and patients suffering from acute and chronic virus hepatitis in various geographical zones of the USSR. HBs Ag/ay proved to prevail (84--100%), HBs Ag/ad was distributed irregularly--from 16% in the European part of the USSR to 0--4% in the republics of the Middle Asia and Siberian regions. HBs Ag/ad was mostly determined in the population of Western regions of the European part of the USSR (the Baltic republics, 43.4%, Moldavia 24.3%).

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Mentioned in this Paper

Hepatitis B Antigens
Antigenic Specificity
Immune Sera
Acute Disease
Phosphoglycerate Dehydrogenase Activity
Human Geography
Hepatitis B Surface Antigens

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