Success rates for product development strategies in new drug development

Journal of Clinical Pharmacy and Therapeutics
E DahlinF Sargeant

Abstract

While research has examined the likelihood that drugs progress across phases of clinical trials, no research to date has examined the types of product development strategies that are the most likely to be successful in clinical trials. This research seeks to identify the strategies that are most likely to reach the market-those generated using a novel product development strategy or strategies that combine a company's expertise with both drugs and indications, which we call combined experience strategies. We evaluate the success of product development strategies in the drug development process for a sample of 2562 clinical trials completed by 406 US pharmaceutical companies. To identify product development strategies, we coded each clinical trial according to whether it consisted of an indication or a drug that was new to the firm. Accordingly, a clinical trial that consists of both an indication and a drug that were both new to the firm represents a novel product development strategy; indication experience is a product development strategy that consists of an indication that a firm had tested previously in a clinical trial, but with a drug that was new to the firm; drug experience is a product development strategy that consist...Continue Reading

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Citations

Dec 31, 2019·The Journal of Medicine and Philosophy·Michael Buckley, Collin O'neil
Aug 30, 2016·Nature Neuroscience·Charles G JenningsGuoping Feng
Jun 7, 2019·Journal of Neurology, Neurosurgery, and Psychiatry·Alexander E CloutRobert D S Pitceathly
Apr 6, 2020·Thérapie·Olivier BlinJoëlle Micallef
Nov 13, 2019··Shintaro SengokuTakeshi Akiyama

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