Successful closure of ileostomy in a patient with intestinal Behçet's disease after therapy with adalimumab: A case report

Medicine
Zhe YanQi-Bing Xie

Abstract

Behçet's disease (BD) is a chronic immune-mediated inflammatory disorder involving multiple organ systems. In BD, intestinal ulcers can present as a refractory lesion capable of perforation, which makes the choice of treatment difficult. A 34-year-old male who was diagnosed with intestinal BD and suffered with an ileocecal perforation. He underwent surgery for an ileostomy and was given corticosteroids as treatment. However, the ulcerative lesion remained resistant to the therapy that was provided which delayed the closure operation. Intestinal BD with severe post-operative complication. A course of adalimumab (ADa) therapy was started. Subsequently surgery was performed. And ADa and thalidomide were used as a maintenance therapy. In this case, a course of ADa therapy was given which healed the intestinal ulcers and allowed us to successfully perform the closure operation. This case indicates that ADa may be an effective treatment option in future cases, minimizing complications and allowing the closure operation to be performed successfully.

References

Feb 19, 2008·Current Opinion in Rheumatology·Ilan Krause, Abraham Weinberger
Apr 9, 2008·Inflammatory Bowel Diseases·Makoto NaganumaToshifumi Hibi
May 14, 2009·The American Journal of Gastroenterology·José A PajaresLuis Menchén
May 25, 2010·Arthritis and Rheumatism·D SaadounP Cacoub
Sep 24, 2014·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Satoshi TanidaToshifumi Hibi
Jun 10, 2015·Clinical Journal of Gastroenterology·Mitsuaki IshiokaHirohide Ohnishi
Dec 13, 2016·Arab Journal of Gastroenterology : the Official Publication of the Pan-Arab Association of Gastroenterology·Aya HammamiAli Jmaa
Jul 4, 2017·Intestinal research·Hyun Jung Lee, Jae Hee Cheon
Dec 7, 2017·The Korean Journal of Internal Medicine·Yong Eun Park, Jae Hee Cheon

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