Successful erythropoietin treatment for severe anemia in nephrotic syndrome without renal dysfunction

Nephron
T IshimitsuS Yagi

Abstract

A 62-year-old woman presented with nephrotic syndrome and severe anemia although the renal function was not impaired. Renal biopsy revealed the histology of membranoproliferative glomerulonephritis, and the proteinuria was resistant to steroid therapy. Iron deficiency, bleeding and other causes of anemia were ruled out, however, her serum erythropoietin level was inappropriately low. The anemia was rapidly corrected by administration of recombinant human erythropoietin. It is suggested that inappropriately low erythropoietin level, in part at least, accounts for the anemia in nephrotic syndrome. It is proposed that erythropoietin therapy should be taken into consideration for severe anemia in nephrotic syndrome even when the renal function is not impaired.

Citations

Sep 1, 2005·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Nina MährKarl Lhotta
Jun 30, 2001·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·N D Vaziri
Aug 1, 2006·La Revue de médecine interne·B TerrierA Hummel
May 29, 2015·International Urology and Nephrology·M PappaK Katopodis
Jun 7, 2005·Expert Opinion on Pharmacotherapy·Hugo Donato
Nov 12, 2005·European Journal of Clinical Investigation·E Ritz, V Haxsen

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