Successful fertilization, embryo development, and pregnancy in human in vitro fertilization (IVF) using a chemically defined culture medium containing no protein

Journal of in Vitro Fertilization and Embryo Transfer : IVF
C M Caro, A Trounson

Abstract

A randomized control trial involving the fertilization and culture of human embryos in culture medium (T6) containing either 10% maternal serum or no protein or amino acid supplement was carried out to assess the effect of deletion from culture of all fixed nitrogen on fertilization, embryo development, and embryo viability. There was no difference in fertilization rates (68 vs 69%), development of apparently normal embryos (96 vs 97%), pregnancy rate (18 vs 14%), or birth rate (13 vs 11%) between protein-containing and protein-free media. Deletion of protein from the culture medium may enable the constitution of more appropriate and defined culture media for human in vitro fertilization (IVF).

References

Sep 1, 1984·Journal of in Vitro Fertilization and Embryo Transfer : IVF·A Trounson, A H Sathananthan
Sep 1, 1984·Journal of in Vitro Fertilization and Embryo Transfer : IVF·C M Caro, A Trounson
Sep 1, 1984·Fertility and Sterility·M M Mahadevan, A O Trounson
Mar 1, 1982·Journal of Reproduction and Fertility·A O TrounsonJ F Leeton
Aug 1, 1982·Fertility and Sterility·J LeetonC Wood
Feb 1, 1965·The Journal of Experimental Zoology·R L BRINSTER

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Citations

Apr 1, 1988·Journal of in Vitro Fertilization and Embryo Transfer : IVF·B AriffR Shan
Jun 1, 1989·Journal of in Vitro Fertilization and Embryo Transfer : IVF·C A BenadivaG L Flickinger
Feb 1, 1986·Journal of in Vitro Fertilization and Embryo Transfer : IVF·L FreemannC Kirby
Jun 1, 1991·Journal of in Vitro Fertilization and Embryo Transfer : IVF·I S TummonA A Yuzpe
Apr 1, 1990·Journal of in Vitro Fertilization and Embryo Transfer : IVF·P V Dandekar, R H Glass
Oct 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·C M CaroC Kirby
Jan 1, 1996·Journal of Assisted Reproduction and Genetics·N N DesaiJ M Goldfarb
Jul 1, 1995·Journal of Assisted Reproduction and Genetics·P S WeathersbeeT Ord
Feb 23, 2013·Journal of Assisted Reproduction and Genetics·Yves MénézoKay Elder
Sep 1, 1990·Theriogenology·M H Javed, R W Wright
Aug 1, 1993·Theriogenology·M Ivanova, M Mollova
Nov 1, 1993·British Journal of Obstetrics and Gynaecology·P VandekerckhoveT W Harada
Aug 1, 1996·American Journal of Reproductive Immunology : AJRI·E G Schneider, C C Hayslip
Apr 2, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Nicolas M Orsi, Henry J Leese
Jul 19, 2014·Human Reproduction Update·Elpiniki Chronopoulou, Joyce C Harper
Jun 1, 1989·American Journal of Obstetrics and Gynecology·K J Ryan
Mar 16, 2007·Journal of Medical Primatology·Catherine A VandeVoortR D Schramm
Jun 27, 2018·Journal of Cellular Physiology·Farshid YekaniHossein Baharvand
Apr 1, 1988·Journal of in Vitro Fertilization and Embryo Transfer : IVF·B D Bavister, J C Andrews
Jan 1, 1993·Journal of Assisted Reproduction and Genetics·A AdlerJ Cohen
Feb 1, 1987·Journal of in Vitro Fertilization and Embryo Transfer : IVF·J M ShawJ F Hennessey
Oct 1, 1986·Journal of in Vitro Fertilization and Embryo Transfer : IVF·M M MahadevanP J Taylor
Jun 1, 1994·Asia-Oceania Journal of Obstetrics and Gynaecology·M Tanikawa

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