Successful medical management of isolated renal zygomycosis: case report and review

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
D E WengT J Walsh

Abstract

We describe the medical management of isolated renal zygomycosis in an adult patient with AIDS during chemotherapy for AIDS-related lymphoma. After initial presentation during the first cycle of chemotherapy, the infection was contained within the kidney following recovery of the neutrophil count without medical or surgical intervention. Since he was not considered to be a candidate for nephrectomy, his infection was treated with amphotericin B lipid complex during subsequent chemotherapy. Neutropenia was minimized by the addition of cytokine support therapy with granulocyte colony-stimulating factor and reduced doses of chemotherapy. Following this strategy, his lymphoma completely resolved, and renal zygomycosis was controlled. At the time of this writing, he had been in complete remission for 18 months without evidence of progressive fungal infection. This report and our literature review indicate that isolated renal zygomycosis can be associated with a favorable prognosis, occurs with greatest frequency in patients with AIDS, is associated with parenteral access, and may be managed by medical therapy alone.

Citations

Mar 29, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·M ChayakulkeereeJ R Perfect
Sep 8, 2001·The Journal of Infection·A ChakrabartiV Sakhuja
Aug 3, 2006·Medical Mycology·Jin Yu, Ruo Yu Li
Jun 15, 2006·Medical Mycology·Arunaloke ChakrabartiVinay Sakhuja
May 19, 2007·Medical Mycology·Joshua PerlrothBrad Spellberg
Jun 14, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·D P KontoyiannisK V Rolston
Aug 5, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maureen M RodenThomas J Walsh
May 14, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Brad SpellbergAshraf S Ibrahim
Jan 25, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George PetrikkosDimitrios P Kontoyiannis
Jan 30, 2008·Antimicrobial Agents and Chemotherapy·Ashraf S IbrahimBrad Spellberg
Jul 16, 2005·Clinical Microbiology Reviews·Brad SpellbergAshraf Ibrahim
Dec 14, 2011·Immunotherapy·Charalampos AntachopoulosEmmanuel Roilides
Apr 1, 2010·Medical Mycology·Federico Palacio-BedoyaThomas F Patterson
Apr 2, 2014·International Journal of Nephrology·Tamim HamdiGeorge J Alangaden
Oct 1, 2012·Journal of Nephropathology·Krishan L Gupta, Aakriti Gupta
May 17, 2012·Medical Mycology·Pierre CharlesOlivier Lortholary
Jun 7, 2014·BMJ Case Reports·Ajay Kr SinghSuresh Kumar
Jun 25, 2014·Future Microbiology·Michaela LacknerCornelia Lass-Flörl
Sep 25, 2014·Indian Journal of Nephrology·L S NayagamS Balasubramanian
Sep 14, 2004·Leukemia & Lymphoma·B GleissnerE Thiel
Jan 30, 2004·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·R M Prabhu, R Patel
Sep 7, 2007·Mayo Clinic Proceedings·Thushan I de SilvaDavid H Dockrell
Aug 8, 2008·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·M E Arnáiz-GarcíaA M Arnáiz-García
Oct 18, 2015·The Urologic Clinics of North America·Lewis Thomas, Chad R Tracy
Dec 11, 2003·The Journal of Urology·Li JianhongJiang Xuewu
Dec 10, 1999·The Urologic Clinics of North America·G J WiseV K Marella
Sep 17, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A Alastruey-IzquierdoJ L Rodríguez-Tudela
Sep 17, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G L Petrikkos
Nov 3, 2011·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A Katragkou, E Roilides
Sep 2, 2008·Diabetes Research and Clinical Practice·Tuba TuruncHande Arslan
Jul 11, 2016·The Journal of Infection·José MoreiraCristiane C Lamas
Sep 14, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Andrew SimmelinkGerald Capraro
Oct 5, 2001·Expert Opinion on Pharmacotherapy·G J Wise
Nov 5, 2003·Expert Opinion on Pharmacotherapy·Peter K Linden
Apr 22, 2005·Dermatologic Therapy·Priya VenkatesanSarah A Myers
Oct 27, 1999·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·K L GuptaV Sakhuja
May 22, 2021·Infectious Disease Clinics of North America·Julie M Steinbrink, Marisa H Miceli
Jan 7, 2003·Infectious Disease Clinics of North America·Corina E GonzalezAlan M Sugar
May 4, 2000·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J A GuardiaJ Diego

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