Successful outcome of ganciclovir-resistant cytomegalovirus infection in organ transplant recipients after conversion to mTOR inhibitors

Transplant International : Official Journal of the European Society for Organ Transplantation
N SabéJordi Carratalà

Abstract

Ganciclovir-resistant (GanR) cytomegalovirus (CMV) infection after organ transplantation is emerging as a significant therapeutic challenge. We report two cases of GanR CMV infection successfully managed by switching immunosuppression from calcineurin inhibitors to an mTOR inhibitor-based regimen. This salvage therapy should be considered when other options are not available.

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Apr 9, 2015·Clinical Kidney Journal·Raquel VazManuel Pestana
Sep 8, 2012·Expert Opinion on Drug Safety·Hallvard HoldaasAnders Åsberg
May 3, 2016·Transplantation Reviews·J Torre-CisnerosUNKNOWN Spanish Network for Research in Infectious Diseases (REIPI)
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Jan 26, 2018·Transplantation·Lyndsey J BowmanChristina T Doligalski
Sep 14, 2018·World Journal of Transplantation·Junji UchidaTatsuya Nakatani

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