Successful pregnancy after localized resection of perforated uterus in choriocarcinoma and a literature review

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
N BehtashF Sarvi

Abstract

Choriocarcinoma is an aggressive neoplasm arising in the body of the uterus. Rapid growth and myometrial invasion may be followed by uterine perforation. In this study, we present the cases of two young patients (18 and 19 years of age) with acute abdominal pain and shock, while they were under chemotherapy due to persistent trophoblastic disease. During emergent exploratory laparotomy, localized resection of uterus was performed. They had their first successful term pregnancy 5 and 4 years after surgery, respectively. Uterine perforation following choriocarcinoma is a rare event. Hysterectomy is recommended in emergency conditions, but localized resection of uterus should be considered in women who are desirous of future fertility.

References

Oct 1, 1996·Obstetrics and Gynecology·G S Leiserowitz, M J Webb
Dec 5, 1996·The New England Journal of Medicine·R S Berkowitz, D P Goldstein
Apr 1, 1997·The Journal of Obstetrics and Gynaecology Research·T OkamotoY Tomoda
Dec 13, 2002·Gynecologic Oncology·Narendra PisalBarry Hancock

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Citations

Mar 17, 2009·Archives of Gynecology and Obstetrics·Vassilios LiberisNikoleta Koutlaki
Aug 19, 2007·Journal of Cancer Research and Clinical Oncology·Nadereh Behtash, Mojgan Karimi Zarchi
Feb 9, 2012·Chemotherapy Research and Practice·Taymaa MayRoss S Berkowitz
Dec 18, 2009·Expert Review of Anticancer Therapy·Fengzhi Feng, Yang Xiang
Dec 23, 2015·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D M ShererO Abulafia
Jan 31, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·K Y Tse, Hextan Y S Ngan
Oct 12, 2011·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Chuan XieXia Zhao
Dec 4, 2009·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Jenny Lynn D C Estrella, Agnes L Soriano-Estrella

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