Successful pregnancy after simultaneous pancreas-kidney transplantation.

Case Reports in Obstetrics and Gynecology
A SmythF Dunne

Abstract

The effect of pregnancy on simultaneous pancreas-kidney transplant recipients has previously been described, but experience is limited. We describe the case of a thirty-five-year-old female who previously underwent simultaneous pancreas-kidney transplant for type 1 diabetes mellitus-complicated nephropathy. An integrated multidisciplinary team including the transplant team, nephrologist, endocrinologist, and obstetrician closely followed progress during pregnancy. Blood glucose levels and HbA1c remained within normal limits, and she did not require insulin treatment at any point. She experienced deterioration in renal indices and underwent an uncomplicated, elective Caesarean section at thirty-week gestation. She delivered a male infant of 1.18 kg, appropriate for gestational age, who had hypothermia and respiratory distress, which required intubation and ventilation and an eleven-week stay in the special care baby unit. At eighteen-month followup the infant shows normal development, and there has been no deterioration in either grafts' function.

References

Apr 12, 1990·The New England Journal of Medicine·W R KennedyJ S Najarian
Sep 1, 1989·Geburtshilfe und Frauenheilkunde·J BaltzerG Lipowsky
Mar 1, 1986·Diabetic Medicine : a Journal of the British Diabetic Association·A GrenfellP J Watkins
Mar 1, 1996·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·J D PirschM R Weir
Feb 12, 1998·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·K MidtvedtG Haugen
Sep 3, 1998·Journal of Transplant Coordination : Official Publication of the North American Transplant Coordinators Organization (NATCO)·C H McGroryV T Armenti
Mar 20, 1999·Transplantation Proceedings·C H McGroryV T Armenti
May 1, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mahboob Lessan-Pezeshki
Apr 20, 2004·The American Journal of Gastroenterology·David Norman MoskovitzDaniel H Present
Jun 10, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Dianne B McKayUNKNOWN Women's Health Committee of the American Society of Transplantation
Oct 11, 2005·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Thorsten FischerKlemens Budde
Mar 24, 2006·The New England Journal of Medicine·Dianne B McKay, Michelle A Josephson
May 23, 2006·Arthritis Research & Therapy·Monika ØstensenAngela Tincani
Dec 7, 2007·Fertility and Sterility·Axel FichezBruno Salle
Mar 31, 2011·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·J R Chapman

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Citations

Sep 23, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Joao C De Pinho, Mark V Sauer
Sep 23, 2020·Journal of Nephrology·Amelia CarettoAntonio Secchi

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