PMID: 59146Jul 10, 1976

Successful renal allografts across a positive cross-match for donor B-lymphocyte alloantigens

Lancet
R B EttingerR N Fine

Abstract

Seven patients received a renal allograft with negative standard and T-lymphocyte microlymphocytotoxicity cross-matches, but a positive B-lymphocyte cross-match using donor lymphocytes. In spite of this presensitisation, none underwent hyperacute rejection and all are functioning from one and a half to six months after transplantation. This procedure may help in the detection of false-positive cross-matches and possibly in detection of enhancing antibodies against a specific donor.

Citations

Sep 1, 1979·Irish Journal of Medical Science·S B MooreP I Terasaki
Jan 1, 1993·Transplant Immunology·D Talbot
Nov 1, 1979·The New England Journal of Medicine·R D Guttmann
Apr 10, 1980·The New England Journal of Medicine·R J DuquesnoyH M Kauffman
Oct 1, 1979·Annals of Surgery·T E StarzlC G Halgrimson
Jan 1, 1992·Scandinavian Journal of Immunology·B SanchezA Nuñez-Roldan
Nov 25, 2003·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Howard M GebelPeter Nickerson
Apr 1, 1989·Transplant International : Official Journal of the European Society for Organ Transplantation·A Ting
Jan 1, 1982·Immunological Reviews·P J Morris, A Ting
May 16, 2008·International Journal of Immunogenetics·D D Eckels
Feb 28, 2003·Transplantation·Stéphanie Le Bas-BernardetJean-Denis Bignon
Jan 1, 1980·Immunological Reviews·P J Morris
Jan 1, 1984·Vox Sanguinis·F DecaryH Mervart
Jan 8, 2017·Journal of the American Society of Nephrology : JASN·Madhav C MenonPeter S Heeger
Jan 1, 1979·American Journal of Hematology·H A Perkins
Jun 1, 1977·Arthritis and Rheumatism·W P ArendG A Starkebaum
Jan 1, 1981·Tissue Antigens·P J Morris, A Ting
Dec 1, 1979·Irish Journal of Medical Science·S B MooreP I Terasaki
Jan 12, 1999·Transplantation·A J Matas, D E Sutherland
Oct 1, 1994·The Journal of Urology·W C WaltzerF T Rapaport

Related Concepts

B-Lymphocytes
SD Antigens
HLA Typing
HLA Antigens
Isoantibodies
T-Lymphocyte
Transplantation, Homologous
Kidney Transplantation

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.