Successful resuscitation following ropivacaine-induced systemic toxicity in a neonate

Anaesthesia
M HüblerT Koch

Abstract

A 5-week-old preterm infant was scheduled for inguinal hernia repair. Following induction of general anaesthesia, 10 mg.kg(-1) ropivacaine was injected, accidently, into the caudal space. The infant developed cardiac depression with bradycardia (minimum heart rate 50 beats.min(-1) ), elevated T waves and widening of QRS complexes. Resuscitation by means of external chest compression, intravenous adrenaline and fluid administration was successful. Ropivacaine serum concentrations were obtained at three time points yielding a peak level of 6 μg.ml(-1) 20 min after caudal injection.

References

Nov 1, 1989·Anesthesia and Analgesia·D B ScottR Lundh
Mar 7, 2000·Anesthesia and Analgesia·S A Kozek-LangeneckerM Semsroth
Oct 12, 2000·Acta Anaesthesiologica Scandinavica·T I Ala-KokkoS Alahuhta
Nov 7, 2000·British Journal of Anaesthesia·P A LönnqvistM Bielenstein
Feb 19, 2002·Paediatric Anaesthesia·Lionel SimonAnne-Marie Dubousset
Jul 16, 2003·Acta Anaesthesiologica Scandinavica·M ReinikainenE Ruokonen
Aug 23, 2003·Anesthesia and Analgesia·Stephen M KleinSusan M Steele
May 6, 2005·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Mathieu GielenNigel Jack
Dec 23, 2006·Anaesthesia and Intensive Care·L P Y Khoo, A R Corbett
Apr 24, 2008·Anesthesiology·Guy L WeinbergDouglas L Feinstein

❮ Previous
Next ❯

Citations

Sep 20, 2011·Paediatric Anaesthesia·Jean-Xavier Mazoit
Jan 5, 2011·Paediatric Anaesthesia·Donald A SchwartzNeil Roy Connelly
Aug 10, 2011·Paediatric Anaesthesia·Martin Jöhr, Thomas M Berger
Apr 12, 2016·Paediatric Anaesthesia·Geoff FrawleyAndrew Bjorksten
Oct 27, 2016·Plastic and Reconstructive Surgery·Donald H Lalonde
Jul 19, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Michael R Fettiplace, Guy Weinberg
May 30, 2017·BMJ Case Reports·Wan Yen LimEvangeline Hua Ling Lim
Aug 16, 2014·Anesthesia and Analgesia·Peter BedocsChester C Buckenmaier
Oct 8, 2014·Plastic and Reconstructive Surgery. Global Open·Sarah Al Youha, Donald H Lalonde

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bradyarrhythmias

Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.