Abstract
A 3-yr-old girl developed severe progressive juvenile laryngeal papillomatosis (JLP) 2 yr after liver transplantation (Tx) for biliary atresia. The papillomata were resistant to withdrawal of immunosuppression, to laser surgery, and to subcutaneous interferon (3 MU/m2, three times weekly), necessitating tracheostomy. Oral ribavirin therapy (25 mg/kg/day) in combination with no immunosuppression effectively prevented the rapid recurrence of JLP over 5 yr. Hence, oral ribavirin is a potentially useful therapy in this life-threatening situation and may also be of benefit in other children with severe JLP.
References
Aug 29, 1991·The New England Journal of Medicine·B G LeventhalD Wold
Jun 1, 1989·Clinical Otolaryngology and Allied Sciences·R E QuineyC B Croft
Mar 1, 1986·European Journal of Epidemiology·H FernandezR Smith
Aug 18, 1988·The New England Journal of Medicine·G B HealyK N Price
Feb 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·M A Avidano, G T Singleton
May 1, 1994·American Journal of Otolaryngology·M KiroğluC Ozsahinoğlu
Apr 1, 1994·Archives of Otolaryngology--head & Neck Surgery·S A EicherD T Donovan
Nov 1, 1993·Head & Neck·R C McGlennenR S Ostrow
Jan 1, 1993·Auris, Nasus, Larynx·T SakohJ Kanzaki
May 1, 1993·The Journal of Laryngology and Otology·G A MorrisonJ N Evans
Mar 1, 1993·International Journal of Pediatric Otorhinolaryngology·A Padayachee, C A Prescott
Mar 1, 1993·Antimicrobial Agents and Chemotherapy·E ConnorJ Connor
Apr 9, 1998·Allergy and Asthma Proceedings·N W WilsonM B Hogan
Nov 10, 1998·Lancet·T PoynardJ Albrecht
Jul 31, 1999·International Journal of Pediatric Otorhinolaryngology·A FerlitoG Marioni
Nov 7, 1999·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·E Rehberg, O Kleinsasser
Citations
Oct 11, 2017·Journal of the Pediatric Infectious Diseases Society·Tomohiro KatsutaKristen A Feemster
Jun 6, 2007·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Neil K Chadha, Adrian L James
Jan 5, 2002·Journal of Clinical Laser Medicine & Surgery