Successful termination of sustained transmission of resident MRSA following extensive NICU refurbishment: an intervention study

The Journal of Hospital Infection
A SempleE Moylett

Abstract

Neonatal sepsis is a leading cause of morbidity and mortality in neonatal units worldwide. Meticillin-resistant Staphylococcus aureus (MRSA) has become a leading causative pathogen. Many neonatal units experience endemic colonization and infection of their infants, which is often very challenging to successfully eradicate. To assess the impact of neonatal unit refurbishment and redesign on endemic MRSA colonization and infection. A retrospective review was carried out over an eight-year period in a 14-cot, level 2-3 neonatal unit in University Hospital Galway, a large university teaching hospital in the West of Ireland. Surveillance, colonization, and infection data for a four-year period pre and four-year period post neonatal unit refurbishment are described. Clinical and microbiological data were collected on all MRSA-colonized and -infected infants between 2008 and 2015. Molecular typing data are available for MRSA isolates. An interrupted time-series design was used, with unit refurbishment as the intervention. Our neonatal unit had a pattern of sustained transmission of endemic resident MRSA strains which we could not eradicate despite repeated standard infection control interventions. Complete unit refurbishment led to su...Continue Reading

Citations

Jul 2, 2021·Antimicrobial Resistance and Infection Control·Qianxing WuEbrahim Kouhsari

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR & Staphylococcus

CRISPR-Cas system enables the editing of genes to create or correct mutations. Staphylococci are associated with life-threatening infections in hospitals, as well as the community. Here is the latest research on how CRISPR-Cas system can be used for treatment of Staphylococcal infections.

Related Papers

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Yhu-Chering HuangTzou-Yien Lin
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Priya BehariStephen G Weber
Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Eric D SchultzP Brian Smith
© 2022 Meta ULC. All rights reserved