PMID: 9558141Apr 29, 1998Paper

Successful therapy of refractory graft versus host disease with tacrolimus and Psoralen plus ultraviolet light

Therapeutic Drug Monitoring
R F Jubran, P A Dinndorf

Abstract

The authors report a patient who developed severe graft versus host disease (GVHD) after undergoing a matched, unrelated bone marrow transplant. Her symptoms worsened despite treatment with cyclosporine, high doses of methylprednisolone, and antithymocyte globulin. After treatment with tacrolimus (FK506) and Psoralen plus ultraviolet light (PUVA), there was complete resolution of all clinical and laboratory evidence of GVHD. This combination may be beneficial to other patients who develop severe GVHD that is resistant to conventional therapy.

References

Oct 27, 1994·The New England Journal of Medicine·UNKNOWN U.S. Multicenter FK506 Liver Study Group
Sep 1, 1995·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J B Weaver
Sep 1, 1995·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·J D Van HornJ M Maisog
Dec 1, 1995·Therapeutic Drug Monitoring·W J JuskoR Lieberman

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Citations

Jan 8, 2000·Dermatologic Clinics·A S Boyd
Apr 24, 2008·American Journal of Clinical Dermatology·Marta Valdivielso-RamosJosé Manuel Hernanz
Nov 1, 2007·Dermatologic Therapy·V Madan, C E M Griffiths
Jan 13, 2001·Dermatologic Clinics·J C CatherA Menter

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