Successful topical rapamycin treatment for facial angiofibromata in two children

Pediatric Dermatology
Emma V PynnJenny Hughes

Abstract

Topical sirolimus, or rapamycin, is known to inhibit tumorigenesis in tuberous sclerosis. We report two cases of successful treatment of children with facial angiofibromata and summarize the encouraging evidence of the effectiveness of this therapy in the literature.

References

Jan 30, 2008·BMC Dermatology·Aubrey RauktysSandra L Dabora
Jul 21, 2010·Archives of Dermatology·Anna K HaemelJoyce M Teng
Aug 13, 2011·Journal of the European Academy of Dermatology and Venereology : JEADV·R SalidoJ C Moreno-Giménez
Feb 9, 2012·The Australasian Journal of Dermatology·Rachael S FosterAnne R Halbert
May 18, 2013·Journal of Child Neurology·James W Wheless, Hassan Almoazen

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