Successful treatment by paroxetine of delusional disorder, somatic type, accompanied by severe secondary depression

Clinical Neuropharmacology
Hiroshi HayashiK Otani

Abstract

The case of a 42-year-old woman with delusional disorder, somatic type (DDST), with infestation delusion and delusions of body odor and halitosis accompanied by severe secondary depression is presented. These somatic delusions and depressive symptoms responded favorably to treatment with paroxetine 10 to 30 mg/d. Hypoperfusion in the left temporal and parietal lobes observed when she had marked clinical symptoms was improved at near recovery. The present report suggests that paroxetine is effective and a reasonable drug for DDST with secondary depression. It also supports previous observations that DDST is associated with hypoperfusion in the temporal and parietal lobes.

References

Jun 16, 1999·Progress in Neuro-psychopharmacology & Biological Psychiatry·T WadaK Otani
Jul 15, 2004·Human Psychopharmacology·Hiroshi HayashiKoichi Otani

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Citations

Oct 1, 2012·Acta Neuropsychiatrica·Yuzuru ShibuyaKoichi Otani
Jul 6, 2010·Progress in Neuro-psychopharmacology & Biological Psychiatry·Roland W FreudenmannCarlos Schönfeldt-Lecuona
Jan 27, 2012·Oral Diseases·C Scully, J Greenman
Jun 25, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·Robert Christian WolfRoland W Freudenmann
Aug 8, 2020·The Psychiatric Quarterly·Alexandre González-Rodríguez, Mary V Seeman
May 14, 2020·World Journal of Psychiatry·Alexandre González-RodríguezMary V Seeman

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