Successful Treatment of a Large Superficial Bladder Cancer with Neoadjuvant Arterial Infusion Chemotherapy: A Case Report

Case Reports in Oncology
Hiroshi KanoKeiichi Kawai

Abstract

We present a case in which neoadjuvant arterial infusion chemotherapy was effective in treating a large superficial bladder cancer. A 50-year-old male was admitted to the Kanazawa Medical Center with the complaint of dizziness. The patient exhibited severe anemia, and his computer tomography showed a large bladder tumor. Cystoscopy revealed a large papillary tumor. Magnetic resonance imaging showed no muscle invasion and no metastasis. To avoid a prolonged operation time and excessive blood loss, we performed neoadjuvant arterial infusion chemotherapy for tumor volume reduction before transurethral resection of the bladder tumor (TUR-BT). The arterial infusion chemotherapy was performed twice, and the tumor size gradually reduced from 275 to 28 cm3. After neoadjuvant chemotherapy, TUR-BT was safely performed without blood transfusion. The tumor was staged as T1 with G1. This is the first report demonstrating that neoadjuvant arterial infusion chemotherapy is effective in treating large superficial bladder cancer and is a possible strategy for bladder preservation.

References

Jan 1, 1987·Cancer Chemotherapy and Pharmacology·H KakizakiK Suzuki
Apr 25, 2008·Scandinavian Journal of Urology and Nephrology·Suresh K Gupta, Nigel J Parr
Sep 8, 2010·Journal of Nippon Medical School = Nippon Ika Daigaku Zasshi·Tsutomu HamasakiYukihiro Kondo
Mar 3, 2015·Journal of the American College of Surgeons·Brian J DaleyOscar D Guillamondegui
May 16, 2017·Canadian Urological Association Journal = Journal De L'Association Des Urologues Du Canada·Matthew TruongEdward Messing

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