PMID: 9423825Jan 10, 1998Paper

Successful treatment of acquired factor VIII inhibitors with cyclosporin

American Journal of Hematology
A G BroxM Pelletier

Abstract

The treatment of Factor VIII inhibitors remains controversial and no standard therapy exists. We describe in this report two consecutive patients with this inhibitor that responded to cyclosporin. Clinical improvement of the bleeding diathesis, a return to normal of the PTT, a decrease in the level of the inhibitor, and a return to normal of the factor VIII level followed use of this drug. We believe that cyclosporin is effective in the treatment of factor VIII inhibitors and deserves further investigation.

References

Feb 16, 1984·The New England Journal of Medicine·A D Steinberg
Aug 1, 1981·British Journal of Haematology·J A SperoU Hasiba

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Citations

Jun 7, 2006·Hematology·Massimo Franchini
Mar 21, 2012·Haemophilia : the Official Journal of the World Federation of Hemophilia·J Pardos-GeaJ Ordi-Ros
Oct 4, 2007·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Yesid AlvaradoEverardo Cobos
Jan 22, 2005·Haemophilia : the Official Journal of the World Federation of Hemophilia·A AggarwalG P Schechter
Jul 13, 2006·Haemophilia : the Official Journal of the World Federation of Hemophilia·H J NgL H Lee
Oct 18, 2002·Blood·Adrian WiestnerGeraldine P Schechter
Apr 3, 2003·British Journal of Haematology·Julio DelgadoAna Villar
Oct 4, 2008·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Antonio De PascalisErasmo Buongiorno
Feb 3, 2009·Clinical Reviews in Allergy & Immunology·Kathleen P Pratt, Arthur R Thompson
Jan 5, 2002·Internal Medicine Journal·S P BurnetP Han
Feb 14, 2004·Haemophilia : the Official Journal of the World Federation of Hemophilia·W Y AuY L Kwong
Jul 27, 2006·American Journal of Hematology·Massimo Franchini
Apr 7, 2007·Journal of Clinical Rheumatology : Practical Reports on Rheumatic & Musculoskeletal Diseases·Bruno OliveiraGlenn Ehresmann
Jan 23, 2014·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Achuta K Guddati, David J Kuter

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