Successful treatment of cryptococcal meningitis with amphotericin B colloidal dispersion: report of four cases.

Antimicrobial Agents and Chemotherapy
G Valero, J R Graybill

Abstract

Four patients with cryptococcal meningitis were treated with amphotericin B colloidal dispersion because of nephrotoxicity from prior treatment with conventional amphotericin B. The limited experience presented here suggests that amphotericin B colloidal dispersion is efficacious for the treatment of cryptococcal meningitis, despite being undetectable in cerebrospinal fluid, and offers a potential therapeutic alternative for patients who cannot tolerate conventional amphotericin B.

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Citations

Apr 20, 2001·Advanced Drug Delivery Reviews·L S Guo
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