Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy.

Pediatric Blood & Cancer
Karen D WrightCarlos Rodriguez-Galindo

Abstract

Trilateral retinoblastoma is characterized by the presence of retinoblastoma with an intracranial tumor. The incidence is low and prognosis poor. Due to the paucity of information regarding successful treatment, we report the case of a 6 month old female referred for leukocoria and found to have an associated suprasellar tumor and pineal enhancement. The patient, treated with standard infant brain tumor therapy, remains alive without signs of active disease 35 months after diagnosis; no surgery or irradiation was used. Early diagnosis of trilateral retinoblastoma may facilitate the use of less intensive therapeutic approaches and result in excellent outcomes in these patients.

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Citations

Mar 13, 2013·Pediatric Radiology·Gregory A BonciAndrei I Holodny
Aug 19, 2011·Pediatric Radiology·Pim de GraafUNKNOWN European Retinoblastoma Imaging Collaboration (ERIC)
Jul 18, 2012·Journal of Neuro-oncology·Firazia RodjanJonas A Castelijns
Dec 2, 2014·Pediatric Clinics of North America·Carlos Rodriguez-GalindoDeborah VanderVeen
Apr 4, 2016·BMC Pediatrics·Simone G A SelistrePatricia Ashton-Prolla
Sep 17, 2015·American Journal of Ophthalmology·Marcus C de JongTero Kivelä
Oct 8, 2016·Orbit·Antony George Francis ThottianGoura Kishor Rath
May 30, 2015·Journal of Child Neurology·Michael V Ortiz, Ira J Dunkel
Aug 18, 2017·Neurosurgical Review·Ryuya YamanakaYasuo Takashima
Jul 2, 2019·Journal of Pediatric Hematology/oncology·Sameer Farouk SaitIra J Dunkel
Apr 4, 2021·Cancers·Armida W M FabiusAnnette C Moll
Apr 6, 2021·Pediatric Blood & Cancer·Samir PatelMatthew J Krasin

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