Successful treatment of Helicobacter pylori-negative gastric MALT lymphoma with rituximab.

Digestive Diseases and Sciences
Nadeem ChaudharySikandar Mesiya

Abstract

Helicobacter pylori infection is strongly associated with low-grade gastric lymphoma, commonly known as mucosa-associated lymphoid tissue (MALT) lymphoma. H. pylori eradication leads to complete remission in 80% of early stage MALT lymphomas. The treatment for early stage H. pylori-negative gastric MALT lymphoma is evolving. Rituximab, a chimeric anti-CD20 antibody, has shown response rates of approximately 50% with minimal toxicity in patients with B-cell non-Hodgkin lymphoma. We describe herein the clinical, endoscopic, and histologic features of a patient with H. pylori-negative gastric MALT lymphoma treated successfully with rituximab.

References

Oct 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P HammelJ C Delchier
Jan 1, 1997·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M KocherH Sack
Aug 15, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·P McLaughlinB K Dallaire
Jun 18, 2003·The American Journal of Gastroenterology·Asyia AhmadBarbara B Frank
Sep 7, 2004·European Journal of Haematology·Holger NückelUlrich Dührsen
Sep 14, 2004·Leukemia & Lymphoma·Yvonne H DattaDavid G Binion
Jan 26, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Giovanni MartinelliEmanuele Zucca

❮ Previous
Next ❯

Citations

Jul 3, 2008·Anti-cancer Drugs·Didier DecaudinLivia Lumbroso-Le Rouic
Apr 23, 2013·Mediators of Inflammation·Magdalena Witkowska, Piotr Smolewski
Jul 11, 2007·Clinical Lymphoma & Myeloma·Cecilio AzarKassem A Barada
Jan 20, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Atul B ShinagareAnn S LaCasce
Mar 23, 2010·Helicobacter·Masahiro AsakaUNKNOWN Japanese Society for Helicobacter Research

❮ Previous
Next ❯

Related Concepts

Related Feeds

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

B-Cell Lymphoma

B-cell lymphomas include lymphomas that affect B cells. This subtype of cancer accounts for over 80% of non-Hodgkin lymphomas in the US. Here is the latest research.