Successful Treatment of Klebsiella pneumoniae Harboring a Klebsiella pneumoniae Carbapenemase Isolated from Lumbar Wound Infection and Blood in a Patient with Hardware Retention

Case Reports in Infectious Diseases
Alan BulbinCarl Urban

Abstract

Infections caused by carbapenem-resistant Enterobacteriaceae, especially carbapenemase producing Klebsiella pneumoniae, represent an urgent threat as outlined by the Centers for Disease Control and Prevention (CDC). We present a 66-year-old male with spinal stenosis who underwent elective L2-pelvis posterior spinal fusion at an outside institution and rapidly developed a complicated infection with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase. This is the first described case of a patient with Klebsiella pneumoniae harboring Klebsiella pneumoniae carbapenemase causing postoperative lumbar wound infection and bacteremia, successfully treated with ceftazidime-avibactam in combination with additional synergistic antibacterials and without hardware removal.

References

Jul 4, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Mario TumbarelloMatteo Bassetti
Jul 1, 2015·Open Forum Infectious Diseases·Haley J MorrillKerry L LaPlante
Jul 22, 2015·Antimicrobial Agents and Chemotherapy·Romney M HumphriesAric Gregson
Dec 17, 2015·Antimicrobial Agents and Chemotherapy·Jean-Marie PagèsWright W Nichols
Sep 15, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ryan K ShieldsM Hong Nguyen
Mar 10, 2017·Virulence·Enrico Maria Trecarichi, Mario Tumbarello
Apr 12, 2017·Antimicrobial Agents and Chemotherapy·Romney M Humphries, Peera Hemarajata

❮ Previous
Next ❯

Software Mentioned

Pip
Tazo
Google Scholar

Related Concepts

Related Feeds

Beta-lactamase Inhibitors

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Beta-lactamase Inhibitors (ASM)

Beta-lactamase inhibitors are a class of antibiotics that inhibit beta-lactamases, a family of enzymes involved in bacterial resistance to beta-lactam antibiotics. Here is the latest research.

Carbapenems (ASM)

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Carbapenems

Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

Related Papers

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
Gary WuSpencer Lee
Enfermedades infecciosas y microbiología clínica
Elisa Torres-Del-PliegoLeonor Del Mar-Periáñez-Párraga
Annales de dermatologie et de vénéréologie
P Wolkenstein
© 2022 Meta ULC. All rights reserved