PMID: 8957958Nov 1, 1996Paper

Successful treatment of non-familial haemophagocytic lymphohistiocytosis with interferon and gammaglobulin

Archives of Disease in Childhood
E J EstlinA D Pearson

Abstract

Two cases of non-familial haemophagocytic lymphohistiocytosis (HLH) are presented in which treatment with interferon alfa and gammaglobulin was associated with complete clinical remission. In one case, serological evidence of recent Epstein-Barr virus infection was found. Natural killer cell activity was within normal limits in both children, compatible with a secondary form of HLH. The combination of interferon alfa and intravenous gammaglobulin requires further evaluation in the treatment of non-familial HLH.

References

Nov 1, 1990·Archives of Disease in Childhood·P GoulderC Hatton
Jun 2, 1988·The New England Journal of Medicine·T C Merigan
May 19, 1988·The New England Journal of Medicine·R S ShapiroA Filipovich
Dec 1, 1994·British Journal of Haematology·W J HirstJ Pritchard
Jan 1, 1994·British Journal of Haematology·H G WatsonA C Parker

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Citations

Apr 22, 2009·Indian Journal of Pediatrics·Shanto PramanikSushmita Banerjee
Mar 28, 2009·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Leticia Castillo, Joseph Carcillo
Jun 4, 2014·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Dennis W SimonE Scott Halstead
Sep 3, 2018·International Journal of Legal Medicine·Hsuan-Yun HuChih-Hsin Pan

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